Publications by authors named "Wanbin Chen"

Article Synopsis
  • Metabolic reprogramming is crucial for understanding the growth and recurrence of liver cancers like hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), but there are still no effective clinical strategies for early screening.
  • A detailed metabolomics study using advanced chromatography techniques identified significant increases in certain lipid metabolites, especially in the glycerophospholipid pathway, in patients with HCC and CCA.
  • The research highlights the role of lipid metabolism in cancer progression and suggests it could be a therapeutic target, paving the way for better early diagnosis and personalized treatment options for these liver cancer patients.
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Article Synopsis
  • In biological control programs, understanding diapause in natural enemy insects like the lady beetle Coccinella septempunctata can enhance their storage and effectiveness in pest management.
  • The study reveals that insulin signaling and the FoxO transcription factor play crucial roles in regulating diapause in these beetles, influencing their development.
  • Application of insulin or RNA interference techniques showed that disrupting insulin signaling triggers a state similar to diapause, helping researchers understand the mechanisms behind insect dormancy.
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Background: Telenomus remus (Nixon) is a dominant natural enemy controlling the invasive pest Spodoptera frugiperda (J. E. Smith).

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Cathepsin L protease, which belongs to the papain-like cysteine proteases family, is an important player in many physiological and pathological processes. However, little was known about the role of in ladybird beetles ( Linnaeus) during diapause. Here, we analyzed the characteristics of () in the females of and its role during the diapause of the ladybeetle.

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(Nixon) is a dominant egg parasitoid of the destructive agricultural pest (J. E. Smith) and so is used in augmentative biocontrol programs in several countries.

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Although , a promising parasitoid of , had been successfully reared on the eggs of in some countries, reports from China have argued that it is infeasible. Notably, studies from China have indicated that eggs could be a candidate host. Therefore, to further evaluate the potential of using eggs as hosts, we compared the development and parasitism of on the eggs of and at temperatures between 20-32 °C.

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Background: Glioblastoma (GBM) is a highly malignant brain tumor with poor survival and prognosis. Randomized trials have demonstrated that chemotherapy improves survival in patients with GBM. This study aims to examine the clinical characteristics that are potentially associated with the efficacy of chemotherapy and the risk factors of GBM.

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Background: Autophagy, a highly conserved cellular catabolic process by which the eukaryotic cells deliver autophagosomes engulfing cellular proteins and organelles to lysosomes for degradation, is critical for maintaining cellular homeostasis in response to various signals and nutrient stresses. The dysregulation of autophagy has been noted in the pathogenesis of cancers. Our study aims to investigate the prognosis-predicting value of autophagy-related genes (ARG) in hepatocellular carcinoma (HCC).

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Human group A rotavirus (RVA) is the leading cause of acute viral gastroenteritis in children under 5 years old worldwide. The aim of this study was to investigate the genotype distribution of RVA in the Midwest of China. Sentinel-based surveillance of acute diarrhea was conducted at Children's Hospital of Chongqing Medical University from 2011 to 2015.

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