Safe and selective anticancer agents from tetrafluorinated azobenzene-imidazolium ionic liquids: Synthesis, characterization, and cytotoxic effects.

A new series of tetrafluorinated azobenzene-imidazolium salts is reported. The azobenzene and imidazolium moieties were functionalized with long alkyl chains and connected via a methylene spacer of varying lengths (n = 3-12). They were characterized using FTIR and NMR spectroscopy, and elemental microanalysis.

Chiral Polymorphic Hydrazine-based Asymmetric Liquid Crystal Trimers with Resorcinol as Linking Group.

Introduction: This is the first report on chiral polymorphic hydrazine-based asymmetric liquid crystal trimers, 1-[4'-(4''-(5-Cholesteryloxy)carbonyl)butyloxy]-3-[N-benzylideneoxy-N'-(4'''-decyloxybenzylidene) hydrazine] butyloxybenzenes, and 1-[4'-(4''-(10-cholesteryloxy)carbonyl)nonyloxy]-3-[N-benzylideneoxy-N'-(4'''- decyloxybenzylidene)hydrazine]butyloxybenzenes., in which the hydrazine and cholesterol arms were connected via two flexible methylene spacers (n = 3-12 units and m = 4 or 9, respectively) to the central resorcinol core.

Materials And Methods: FT-IR, 1D and 2D NMR spectroscopy, and CHN microanalysis were used to elucidate the structures of the trimers.

Photoresponsive behavior of hydrophilic/hydrophobic-based novel azobenzene mesogens: synthesis, characterization and their application in optical storage devices.

Three series of alkoxy chain-bearing azobenzene-derived quaternary ammonium iodides with an alkoxy chain at one end, namely ,-diethanol-6-(4-((4'-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides, -ethyl--ethanol-6-(4-((4'-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides and ,-diethyl-6-(4-((4'-alkyloxyphenyl)diazenyl)phenoxy)hexan-1-ammonium iodides were synthesized and characterized. Their mesomorphic and photoswitching properties were examined polarising optical microscopy (POM), differential scanning calorimetry (DSC) and UV-vis spectrophotometry. The liquid crystalline tilted schlieren texture of smectic C, non-tilted natural focal conic texture of smectic A and smectic B phases were observed in the ,-diethanol- and -ethyl--ethanol-bearing ammonium group substituted at the terminal the alkoxy chain of the azo moiety.

New para-substituted non-symmetric isoflavones for their fast photo-switching ability: synthesis and their liquid crystal characterization.

The first example of non-symmetric isoflavone-based fast photo-switchable liquid crystals with different functional groups at the terminal position were synthesized and characterized. Polarizing optical microscopy study revealed that the compounds showed least ordered nematic phase. Optical photo switching study exhibited very fast photoisomerization effect in solution.

Chemical constituents and biological activities of the genus Subergorgia.

The genus Subergorgia (coelenterata, Gorgonacea, Subergorgiidae) is distributed in the Indo-pacific region. Previous investigations on the various species of the genus have revealed the presence of a number of new compounds including alkaloids, sesquiterpenes, diterpenes, and steroids. Certain biological activities particularly cytotoxic activity have been observed for the isolated constituents and compositions derived from the coral.