Publications by authors named "Wan-Na Yang"
Single-nucleotide polymorphisms of and -induced liver injury in the Han Chinese population.
World J Gastroenterol
March 2020
Article Synopsis
- A study was conducted to investigate single-nucleotide polymorphisms (SNPs) that could indicate a person's susceptibility to herb-induced liver injury (PM-DILI) in China, where this is a significant health issue.
- Researchers analyzed genetic data from 382 participants, including patients with PM-DILI, other types of drug-induced liver injury, and healthy controls, to identify SNPs associated with PM-DILI.
- Results revealed three SNPs, particularly rs1055348, had significantly higher frequencies in PM-DILI patients and may serve as a specific risk factor for this condition, suggesting its potential as a biomarker for both PM-DILI and other drug-induced liver injuries.