Publications by authors named "Wan-Fang Chou"
J Proteome Res
March 2024
Article Synopsis
- - Mass spectrometry (MS) is crucial for profiling plasma proteins and discovering disease biomarkers, but challenges arise due to the vast variety of plasma protein concentrations and technical variability in protein quantitation.
- - The study compared the performance of two mass spectrometers, timsTOF HT and timsTOF Pro 2, revealing that timsTOF HT significantly increased the identification of plasma peptide precursors and quantifiability, especially when using the Proteograph for deep protein sampling.
- - In an analysis of plasma samples from late-stage lung cancer patients and controls, timsTOF HT showed a notable increase in the detection of distinct plasma peptide precursors, highlighting its potential to enhance biomarker discovery in larger studies.
