The study explored the effectiveness of combining bioactive glass with rhBMP-9 on rat bone marrow stem cells and compared bone regeneration using different delivery methods.
Scanning electron microscopy and ELISA were used to assess the properties of bioglass and the release of rhBMP-9, while cell behavior and bone growth were measured through various assays and imaging techniques.
Results showed that bioglass enhanced the release of rhBMP-9 and significantly improved cell viability and bone formation compared to bioglass alone, with the best regeneration observed in the samples using both bioglass and rhBMP-9.