Publications by authors named "Wan Li Ye"
The Editors of JBUON issue an Expression of Concern to 'Amarogentin secoiridoid inhibits in vivo cancer cell growth in xenograft mice model and induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway', by Jian-Guo Zhao, Ling Zhang, Xiao-Jun Xiang, Feng Yu, Wan-li Ye, Dong-Ping Wu, Jian-Fang Wang, Jian-Ping Xiong, JBUON 2016;21(3):609-617; PMID:27569081. Following the publication of the above article, readers drew to our attention that part of the data was possibly unreliable. We sent emails to the authors with a request to provide the raw data to prove the originality, but received no reply.
View Article and Find Full Text PDFObjective: The primary purpose of this study is to investigate the effect of hedgehog-interacting protein (HHIP) overexpression on the proliferation, migration and invasion of non-small cell lung cancer (NSCLC).
Methods: Firstly, HHIP gene expression data of NSCLC tissues and normal tissues were obtained from GSE18842/GSE19804/GSE43458 databases of the Gene Expression Omnibus (GEO) database and then validated by TCGA NSCLC database in a cohort of 1027 cases of NSCLC patients and 108 cases of normal people. A chi-square test was used to analyze the relationship between HHIP expression and clinicopathological characteristics of NSCLC.
Article Synopsis
- The article originally published in Volume 21, issue 3 had an incorrect first affiliation listed.
- The incorrect affiliation was attributed to a department in Turkey, while the correct one is associated with a hospital in China.
- This error was present only in the PubMed database, not in the print version of the journal.
Article Synopsis
- The study explored the anti-cancer effects of amarogentin on SNU-16 human gastric cancer cells and in nude mice models, focusing on cell death, growth phases, and specific signaling pathways.
- Results showed that amarogentin caused significant cell death in a dose- and time-dependent way, affected cell appearance, and halted cell cycle progression, especially during the G2/M phase.
- The in vivo experiments revealed that mice treated with amarogentin had much smaller tumors compared to control mice, indicating strong anti-tumor potential which operates through apoptotic mechanisms.
[Concurrent chemoradiotherapy for locally advanced unresectable extrahepatic cholangiocarcinoma: a report of 19 cases].
Zhejiang Da Xue Xue Bao Yi Xue Ban
November 2014
Objective: To evaluate the efficacy and toxicity of concurrent chemoradiotherapy for patients with locally advanced unresectable extrahepatic cholangiocarcinoma.
Methods: Thirty-eight patients with locally advanced unresectable extrahepatic cholangiocarcinoma admitted in Shaoxing People's Hospital from February 2007 to February 2012 were enrolled in the study. They were randomized into sequential chemoradiotherapy (n=19) or concurrent chemoradiotherapy group (n=19).