Probing -Octyl α-d-Glycosides Using Deuterated Water in the Lyotropic Phase by Deuterium NMR.

The lyotropic phase behavior of four common and easily accessible glycosides, -octyl α-d-glycosides, namely, α-Glc-OC, α-Man-OC, α-Gal-OC, and α-Xyl-OC, was investigated. The presence of normal hexagonal (H), bicontinuous cubic (V), and lamellar (L) phases in α-Glc-OC and α-Man-OC including their phase diagrams in water reported previously was verified by deuterium nuclear magnetic resonance (H NMR), via monitoring the DO spectra. Additionally, the partial binary phase diagrams and the liquid crystal structures formed by α-Gal-OC and α-Xyl-OC in DO were constructed and confirmed using small- and wide-angle X-ray scattering and H NMR.

Swelling of Bicontinuous Cubic Phases in Guerbet Glycolipid: Effects of Additives.

Inverse bicontinuous cubic phases of lyotropic liquid crystal self-assembly have received much attention in biomedical, biosensing, and nanotechnology applications. An Ia3d bicontinuous cubic based on the gyroid G-surface can be formed by the Guerbet synthetic glucolipid 2-hexyl-decyl-β-d-glucopyranoside (β-Glc-OC6C10) in excess water. The small water channel diameter of this cubic phase could provide nanoscale constraints in encapsulation of large molecules and crystallization of membrane proteins, hence stresses the importance of water channel tuning ability.