Unlabelled: Both conventional and alternative medical therapies are used by patients to treat low back pain, a condition that affects approximately 33% of the U.S.
Population: Little is known about patients' perceptions of conventional versus alternative therapies.
Purpose: The purpose of this article is to review basic science studies using various animal models for rotator cuff research and to describe structural, biomechanical, and functional changes to muscle following rotator cuff tears. The use of computational simulations to translate the findings from animal models to human scale is further detailed.
Methods: A comprehensive review was performed of the basic science literature describing the use of animal models and simulation analysis to examine muscle function following rotator cuff injury and repair in the ageing population.
Background: Over 30 years ago, Feagin and Curl reported on the diagnosis and treatment of "isolated" injuries of the anterior cruciate ligament (ACL). The purpose of this study was to evaluate the long-term results of the patients initially diagnosed with tears of the ACL, with special emphasis on those treated with primary repair.
Hypothesis: Long-term results are unsatisfactory for open evaluation and treatment of ACL injuries with or without primary repair.
Purpose: Anterior cruciate ligament (ACL) reconstruction is a common procedure that has a fairly high success rate. Despite such success, controversy exists with regard to fixation and graft type. The purpose of this study was to quantify the maximum load to failure for staple-anchor freeze-dried Achilles tendon allograft fixation compared with interference screw bone-pattelar tendon-bone autograft fixation at the time of insertion for ACL reconstruction.
View Article and Find Full Text PDFBrachial plexus injuries commonly occur in athletes participating in contact sports. The incidence of transitory brachial plexus injury is approximately 30% to 50% over the course of a high school, college, or professional football player's career. These injuries are called "stingers" or "burners" because of the associated tingling that occurs in the upper extremity after the injury.
View Article and Find Full Text PDFA concussion is defined as a complex pathophysiologic process affecting the brain that is induced by traumatic biomechanical forces. Concussions are caused by a direct or indirect blow that leads to a graded set of syndromes characterized by functional rather than structural disturbances to the brain. Concussions are characterized by a wide variety of presenting symptoms, including loss of consciousness, amnesia, confusion, headache, and nausea.
View Article and Find Full Text PDFGlucose-dependent insulinotropic peptide (GIP) is an incretin hormone that rises rapidly in response to nutrient ingestion. The GIP receptor is widely expressed in the brain including the brain stem, telencephalon, diencephalon, olfactory bulb, pituitary, and cerebellum. Until recently it was not clear what the endogenous ligand for this receptor was because no GIP expression had been demonstrated in the brain.
View Article and Find Full Text PDFThe mechanisms underlying age-related loss of muscle and bone tissue are poorly understood but are thought to involve changes in sex hormone status, physical activity, and circulating levels of inflammatory cytokines. This study attempts to develop an animal model useful for evaluating these mechanisms in vivo. Male C57BL/6 mice were included for study at 3, 6, 12, 18, 24, and 29 months of age.
View Article and Find Full Text PDFPurpose: To compare the economic costs associated with anterior cruciate ligament (ACL) reconstruction using either autograft or allograft. The surgical costs are reported, including charge categories, for each procedure. All operations were performed in the Southern United States of America.
View Article and Find Full Text PDFPurpose: To prospectively compare outcomes of primary anterior cruciate ligament (ACL) reconstruction with either Achilles tendon allograft with soft-tissue fixation or standard bone-patellar tendon-bone autograft with interference screw fixation.
Type Of Study: Prospective comparative case series.
Methods: A group of 41 patients who underwent soft-tissue allograft reconstruction and a group of 118 patients who underwent autograft bone-patellar tendon-bone reconstruction were included in the final results.
Forty-eight injured adolescent athletes completed questionnaires over 3 months after injury to assess psychosocial outcomes. Depressive symptoms decreased over time, and the lack of positive stress and high athletic identity were associated with early depressive symptoms after accounting for injury severity. Increased social support was associated with lower initial depressive symptoms.
View Article and Find Full Text PDFJ Bone Joint Surg Am
September 2002
Background: Ice is applied following a soft-tissue injury on the basis of clinical information. This study investigates the relationship between ice therapy (cryotherapy) and edema by determining microvascular permeability before and after contusion with and without ice therapy and provides data supporting a reduction in edema following cryotherapy.
Methods: A dorsal microvascular chamber was created in rats to allow the direct examination of microvascular parameters in intact, pre-established microvascular beds of the cutaneous maximus muscle in conscious rats.