Early removal of postmastectomy drains is not beneficial: results from a halted randomized controlled trial.

Background: Closed-suction drainage to reduce seromas is standard after mastectomy. This study evaluates the safety of early drain removal.

Methods: Women undergoing mastectomy were randomized to early removal on postoperative day 2 or standard removal (< 30 mL drainage in 24 hours or postoperative day 14).