Near-Infrared Fluorescent Probes with Amine-Incorporated Xanthene Platforms for the Detection of Hypoxia.

Three fluorescent probes , , and that function in the near-infrared wavelengths and utilize pseudo xanthene platforms with an oxygen atom at the 10-position replaced by a [Me-N] group have been created to identify hypoxia via nitroreductase determinations at the 0.04, 0.10, and 0.