Publications by authors named "Walter M A Westerink"
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Synopsis of recent research by authors named "Walter M A Westerink"
- Walter M A Westerink's recent research primarily focuses on the development and validation of alternative testing strategies for assessing the skin sensitization and genotoxicity of chemicals, emphasizing non-animal methods to improve safety evaluations in drug development and regulatory settings.
- His notable studies include the kinetic direct peptide reactivity assay (kDPRA), which evaluates the reactivity of test substances towards synthetic peptides, and high-content screening assays for genotoxicity using metabolically competent cell lines like HepG2.
- Westerink's work aims to enhance the reliability of in vitro assays for chemical safety testing, providing robust methodologies that can potentially replace traditional animal testing, thereby aligning with regulatory requirements such as the REACH Regulation.
