Objective: The purpose of this study was to compare the outcomes of patients with twin-twin transfusion syndrome who were treated with either serial amniocentesis or selective laser photocoagulation of communicating vessels according to disease severity (stage).
Study Design: Centers that were experienced in the treatment of twin-twin transfusion syndrome were invited to share stage-based perinatal outcome data. All patients met basic standard sonographic criteria for twin-twin transfusion syndrome (polyhydramnios maximum vertical pocket, > or =8 cm; oligohydramnios maximum vertical pocket, < or =2 cm).
A 28-year-old woman underwent surgical repair of spontaneous ruptured membranes at 17 weeks' gestation. A collagen graft was placed endoscopically over the membrane defect located over the internal os. Membranes re-ruptured 14 days later, but the patient did not deliver until 30.
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