Evaluation of 6 years of eHealth data in the alcohol use disorder field indicates improved efficacy of care.

Background: Predictive eHealth tools will change the field of medicine, however long-term data is scarce. Here, we report findings on data collected over 6 years with an AI-based eHealth system for supporting the treatment of alcohol use disorder.

Methods: Since the deployment of Previct Alcohol, structured data has been archived in a data warehouse, currently comprising 505,641 patient days.

qRT-PCR analysis of CEACAM5, KLK6, SLC35D3, MUC2 and POSTN in colon cancer lymph nodes-An improved method for assessment of tumor stage and prognosis.

One fourth of colorectal cancer patients having curative surgery will relapse of which the majority will die. Lymph node (LN) metastasis is the single most important prognostic factor and a key factor when deciding on postoperative treatment. Presently, LN metastases are identified by histopathological examination, a subjective method analyzing only a small LN volume and giving no information on tumor aggressiveness.

Inertial focusing with sub-micron resolution for separation of bacteria.

In this paper, we study inertial focusing in curved channels and demonstrate the alignment of particles with diameters between 0.5 and 2.0 μm, a range of biological relevance since it comprises a multitude of bacteria and organelles of eukaryotic cells.

The ghost in the machine - Is musculoskeletal medicine lacking soul?

In recent times there have been, concurrently, increasing volumes of research questioning whether biomechanics have any relevance at all to musculoskeletal medicine; and a blossoming field of Pain Science identifying that perception of, and context for, pain is often more important than the tissues generating the pain in the first instance. From the academic world to social media, much excitement has been generated in supporting this new direction. However, most of the great work arising from the Pain Science arena is focused on pain itself and on the patients' conscious beliefs around their pain.

Descending pronation patterns.

This practical paper is a continuation of previous papers presented in this section discussing over-pronation. The focus of this article is the way that the body has evolved to handle pronation forces in a descending manner from trunk to foot. It was written to accompany the "Toe-tal Function" editorial in the 20:2 edition of JBMT, but didn't make it in for publication.

The Synchronization of Replication and Division Cycles in Individual E. coli Cells.

Isogenic E. coli cells growing in a constant environment display significant variability in growth rates, division sizes, and generation times. The guiding principle appears to be that each cell, during one generation, adds a size increment that is uncorrelated to its birth size.

Don't get caught flat footed - how over-pronation may just be a dysfunctional model.

For many years there has been a long-held clinical belief that a flat or over-pronating foot should be supported; yet in every other part of the body it has long been recognised that use of support (if at all) should generally be limited to acute rehabilitation. Why should the foot be any different? To support a biological structure, in the long term, is to weaken it. Panjabi's model of joint stability offers insight into why the idea of arch support, as well-intentioned as it may have been, may be a dysfunctional model.