Publications by authors named "Walid Waked"

Recombinant human bone morphogenetic proteins (rhBMPs) are often used during spine surgery, but their effects on postoperative infections have not been well elucidated. Long-bone studies suggest that BMPs may limit local infection and facilitate bone formation. Until now, rhBMP-2 had not been evaluated in the setting of infected spinal arthrodesis.

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Autologous bone grafting remains the gold standard for bone grafting in clinical practice. Although it has withstood the test of time, it remains associated with multiple comorbidities. The search for an alternative bone graft substitute harnessing bone's osteoconductive, osteoinductive, and osteogenic properties remains a challenge.

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Study Design: The study design consisted of a New Zealand white rabbit model of pseudarthrosis repair. Study groups consisting of no graft, autograft, or recombinant human bone morphogenetic protein-2 (rhBMP-2) with absorbable collagen sponge (ACS) or compression resistant matrix (CRM) were evaluated.

Objective: To evaluate the relative efficacy of bone graft materials (autograft, ACS, and CRM).

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Orthopaedic procedures rely on strict sterilization techniques to prevent surgical site infections. Surgical instrument trays are wrapped for sterilization, and these wraps routinely are inspected by operating room personnel to evaluate for breaches before using the contained instruments. The sensitivity of this practice for detecting wrap defects has not been established.

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