Combined microneedling with tacrolimus vs tacrolimus monotherapy for vitiligo treatment.

Background: Miconeedling has been used to augment the transdermal drug delivery. Combination modalities may accelerate and improve the repigmentation in vitiligo.

Objective: To determine the efficacy and tolerability of combined microneedling with tacrolimus vs tacrolimus 0.

Efficacy of microneedling combined with tacrolimus versus either one alone for vitiligo treatment.

Background: Combination therapies have reported to augment the repigmentation in vitiligo. Microneedling (Mn) facilitates drug delivery across the skin barrier.

Objective: To evaluate and compare the efficacy and safety of Mn combined with tacrolimus vs Mn alone or tacrolimus 0.