Sediment-redox dynamics in an oligotrophic deep-water lake in Tierra del Fuego: insights from Fe isotopes.

Unlabelled: For long time in the history of Earth, ferruginous conditions governed the oceans. With the rise of oxygen during the Proterozoic era and the subsequent evolution of living organisms, worldwide deposition of iron formations occurred. These sedimentary units reveal the transition into oxic oceans, passing by local and transitory euxinic conditions, especially in coastal shelves.

Investigating the impact of climate change on the lake ecosystem during the late Holocene using a sedimentary record from the southern Arabian Desert, Yemen.

Lake systems respond physically, chemically, and biologically to hydro-climatic change and variability, and these responses are documented in the sediments. Individual proxies and lacustrine environments may respond to climate variations in a nonlinear way, making it difficult to determine the direction and extent of a climatic shift. Here we investigate the response of lake ecosystem to climatic and environmental changes using a suite of paleo-proxies including ostracods, chironomids, and n-alkanes distribution from paleolake 'Gayal el Bazal (Yemen)'.

Giant paleo-seafloor craters and mass wasting associated with magma-induced uplift of the upper crust.

Giant seafloor craters are known along many a continental margin with recurrent mass-wasting deposits. However, the impact of breakup-related magmatism on the evolution of such craters is barely understood. Using high-quality geophysical datasets, this work examines the genetic relationship among the location of magmatic sills, forced folds and the formation of giant paleo-seafloor craters underneath an ancient mass-transport complex in the Møre and Vøring basins, offshore Norway.

A 220,000-year-long continuous large earthquake record on a slow-slipping plate boundary.

Large earthquakes (magnitude ≥ 7.0) are rare, especially along slow-slipping plate boundaries. Lack of large earthquakes in the instrumental record enlarges uncertainty of the recurrence time; the recurrence of large earthquakes is generally determined by extrapolation according to a magnitude-frequency relation.

Two-step closure of the Miocene Indian Ocean Gateway to the Mediterranean.

The Tethys Ocean was compartmentalized into the Mediterranean Sea and Indian Ocean during the early Miocene, yet the exact nature and timing of this disconnection are not well understood. Here we present two new neodymium isotope records from isolated carbonate platforms on both sides of the closing seaway, Malta (outcrop sampling) and the Maldives (IODP Site U1468), to constrain the evolution of past water mass exchange between the present day Mediterranean Sea and Indian Ocean via the Mesopotamian Seaway. Combining these data with box modeling results indicates that water mass exchange was reduced by ~90% in a first step at ca.

Cataract Surgery in High Hyperopia.

Background: Although cataract surgery is a well-established and standardised procedure, it can be demanding and associated with higher complication rates in high hyperopia. We present clinical data for highly hyperopic patients who underwent cataract surgery over a 12-year period (2005 - 2016) and at a single centre.

Patients And Methods: Out of a total of 11 434 cataract operations, 41 highly hyperopic eyes (SN60AT ≥ 31 dpt) were included for analysis.

The prognostic value of retinal vessel analysis in primary open-angle glaucoma.

Purpose: To analyse a prognostic value of initial retinal vessel flicker response for the 3-year development of functional (visual field) and morphological (nerve fibre layer thickness) damage progression in primary open-angle glaucoma patients.

Patients And Methods: Initially, 70 patients were recruited, and flicker response was measured by standardized procedure with the retinal vessel analyser (RVA). Ocular coherence tomography of retinal nerve fibre layer (OCT RNFL) and a visual field testing were performed at beginning and every 6 months for 3 years; 56 patients completed the study.

Retinal neurovascular coupling in patients with glaucoma and ocular hypertension and its association with the level of glaucomatous damage.

Purpose: To analyze neurovascular coupling in the retina of untreated primary open-angle glaucoma (POAG) and ocular hypertension (OHT) patients.

Patients And Methods: Maximal vessel dilation in response to flicker light was analyzed with Retinal Vessel Analyzer (RVA) in temporal superior/inferior arterioles and veins in 51 POAG patients, 46 OHT and 59 control subjects. RVA parameters were compared between groups, between contralateral POAG eyes, and correlated to intraocular pressure, visual field mean defect and retinal nerve fiber layer thickness.

Association between risk factors and glaucomatous damage in untreated primary open-angle glaucoma.

Purpose: To analyze an association between the presumed risk factors for glaucoma and the actual extent of glaucomatous damage in untreated primary open-angle glaucoma.

Patients And Methods: In 50 untreated open-angle glaucoma patients, we analyzed an association between the level of glaucomatous damage and presumed glaucoma risk factors: mean untreated intraocular pressure (IOP) and short-term IOP variability, ocular pulse amplitude, corneal thickness, acral and corneal temperature, retinal arterial diameter and retinal venous diameter, choroidal blood flow (laser Doppler flowmetry flow, velocity, volume), heart rate, and ocular perfusion pressure. Morphologic damage (mean retinal nerve fiber layer thickness, measured by ocular coherence tomography) and functional damage (visual field mean defect) were evaluated separately in 2 forward-stepwise multiple regression models.

Dynamics of retinal vessel response to flicker light in glaucoma patients and ocular hypertensives.

Purpose: To analyze dynamics of retinal vessel dilation response to flicker light in patients with glaucoma and ocular hypertension.

Patients And Methods: Response to flicker light was measured in retinal vessels by means of Retinal Vessel Analyzer. After the baseline 50 seconds long diameter recording of inferior and superior temporal artery and vein, three flicker stimulations of 20 seconds duration was applied, with a 80 seconds break in between.

Increased prevalence of obstructive sleep apnoea in patients with Charcot-Marie-Tooth disease: a case control study.

Obstructive sleep apnoea (OSA) has previously been described in a large family suffering from Charcot-Marie-Tooth disease type 1 (CMT1). In the present study, we used a case control design to establish whether this suggested link between OSA and CMT1 may also be found when studying genetically non-related patients. 12 patients with CMT1 and 24 control patients matched for age, sex and body mass index (BMI) were included in the study.