Publications by authors named "Waldiney Pires Moraes"

Article Synopsis
  • Cyperus articulatus L. (priprioca) is traditionally used in the Amazon for its aromatic properties and medicinal benefits, particularly for treating inflammatory diseases using its rhizomes.
  • This study explores the phytochemistry and the anti-inflammatory and pain-relieving (antinociceptive) effects of its essential oil (CAEO) through laboratory tests on cells and living mice.
  • Results indicated that CAEO significantly reduced inflammatory markers in cell cultures and lowered leukocyte migration and pain responses in mice, highlighting its potential as a natural remedy for inflammation and pain.
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Introduction: The onset of the COVID-19 pandemic brought about global uncertainties and fears, escalating the dissemination of fake news. This study aims to analyze the impact of fake news on COVID-19 vaccine adherence among pregnant women, providing crucial insights for effective communication strategies during the pandemic.

Methods: A cross-sectional, exploratory study was conducted with 113 pregnant women under care at a Women's Health Reference Center.

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The emergence of SARS-CoV-2, leading to the widespread outbreak of COVID-19, has unveiled a spectrum of symptoms and severe health complications, challenging healthcare systems and impacting millions of lives worldwide. To analyze events allegedly attributable to vaccination or immunization (ESAVI) against SARS-CoV-2 (COVID-19) in the municipality of Santarém, in the interior of the state of Pará, an epidemiological, descriptive study was conducted using data from e-SUS Notifica in Santarém/PA from January 2021 to January 2022. The analyzed data for ESAVI cases included the administered immunobiologicals (Coronavac, Covishield, and Comirnaty), the type of event, case progression, time in days between immunobiological administration, and symptom onset, causality, and classification of ESAVI according to the vaccine package inserts.

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Leprosy is an infectious disease characterized by slow and chronic evolution, caused by Mycobacterium leprae and or Mycobacterium lepromatosis, an intracellular alcohol-acid-resistant (BAAR) bacillus. The objective of this study was to provide an epidemiological, clinical, and geographic characterization of leprosy in the city of Santarém-Pará during the period 2011-2020. A cross-sectional, descriptive, and quantitative approach was used, employing maps and tables to illustrate clinical and epidemiological variables, including: sex, age, race, area of residence, operational classification, clinical form, number of skin lesions, number of affected nerves, and health units.

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Oral diseases are one of the biggest public health problems worldwide, caused by opportunistic pathogens such as and . (priprioca) is a plant conventionally used in traditional medicine in the Amazon region. However, little is known about the possible dentistry-related uses of extracts from the rhizomes and solid waste generated by the extraction of essential oils from this vegetable.

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Rabies, caused by the Lyssavirus genus, is a highly lethal zoonotic disease transmitted by animals such as bats and domestic and wild carnivores to humans, claiming nearly 100% of lives. In Brazil, recent evidence suggests an increasing role of bats in human deaths from rabies, particularly in the Amazon region. This neglected tropical disease disproportionately affects impoverished and vulnerable populations in rural areas, where approximately 80% of human cases are concentrated.

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Malaria is an infectious and parasitic disease caused by protozoa of the genus , which affects millions of people in tropical and subtropical areas. Recently, there have been multiple reports of drug resistance in populations, leading to the search for potential new active compounds against the parasite. Thus, we aimed to evaluate the in vitro antiplasmodial activity and cytotoxicity of the hydroalcoholic extract of Jucá ( in serial concentrations.

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Ducke is a popularly known species known as copaíba that is widely spread throughout the Amazon region. The tree yields an oleoresin which is extensively used in local traditional medicine mainly as an anti-inflammatory and antinociceptive agent. The aim of the present study was to assess the anti-inflammatory potential of this oleoresin obtained from a national forest in the central Amazon which presented an unusual chemical composition.

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Article Synopsis
  • L. (Priprioca) is a plant from the Amazon known for its traditional medicinal uses, and its essential oil contains various terpene compounds, but there's limited information on the solid waste from its oil extraction.
  • This study examined the chemical makeup of these solid residues and tested their potential to inhibit cancer cell growth using mouse and human cell models.
  • Findings revealed that the ethanolic extract from the solid waste decreases cancer cell proliferation with minimal toxicity to healthy cells, suggesting potential therapeutic applications.
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