Analysis of effect isoxsuprine hydrochloride and nicotine in the Transverse Rectus Abdominis Myocutaneous flap (TRAM) in rats.

Purpose: To evaluate the effects of isoxsuprine and nicotine on TRAM.

Methods: Forty eight 48 Wistar rats distributed into four Groups (n=12). All rats received medication managed daily for 20 days: saline solution (SA), nicotine solution (NI), isoxsuprine solution (IS) and nicotine solution (NI) + isoxsuprine solution (IS).

Histology of the rectus abdominis muscle in rats subjected to cranial and caudal devascularization.

Purpose: To investigate the microscopic changes in the rectus abdominis muscle in rats subjected to five delay procedure.

Methods: 30 male Holtzmann rats, weighting between 250 and 350 grams, were used. The animals were divided into five groups (n=6): A - cranial section of the right muscle; B - caudal section of the right muscle; C - craniocaudal section of the right muscle; D - cranial section reflecting the right muscle in the craniocaudal direction; E - caudal section reflecting the right muscle in the caudocranial direction.