Cervical digital photography for screening of uterine cervix cancer and its precursor lesions in developing countries.

Purpose: This study aims to evaluate and to compare the performance of cervical digital photography (CDP) to the visual inspection with acetic acid (VIA) and visual inspection with Lugol's iodine (VILI) methods for screening the uterine cervix cancer and its precursor lesions in developing countries.

Methods: A cross-sectional study was performed in Brazil. 176 women were evaluated by VIA, VILI, CDP with acetic acid and CDP with Lugol's iodine.

Minimal cold knife conization height for high-grade cervical squamous intraepithelial lesion treatment.

Objectives: To assess the relationship between cold-knife conization specimen height, cervical intraepithelial neoplasia (CIN II/III) size and endocervical margin involvement by CIN II/II.

Study Design: A cross-sectional study was performed. Cold knife cone specimens with a diagnosis of CIN II/III were selected.

Comparison of loop electrosurgical conization with one or two passes in high-grade cervical intraepithelial neoplasias.

The use of loop electrosurgical conization (LEC) for the treatment of large high-grade cervical intraepithelial neoplasias (CINs) is often associated with a difficult procedure that results in accidental sample fragmentation, thermal damage and sometimes the presence of positive margins. This study aims to compare LEC that removes the cervical cone in two blocks (anterior and posterior cervical lips - LEC2) with LEC performed with one pass of the loop (LEC1). In a randomized, controlled trial, patients that needed conization due to high-grade CIN were assigned to one of the techniques.

P53 and BCL-2 as prognostic markers in endometrial carcinoma.

The objective of this study was to verify the frequency of p53 and BCL-2 immunohistochemical expression in patients with endometrial carcinoma and to correlate it with histological factors (histological type, tumor grade, depth of myometrial invasion, lymph node involvement and surgical staging) and survival. Forty-eight patients with endometrial carcinoma who were submitted to primary surgical treatment were assessed. p53 and BCL-2 immunohistochemical expression was determined using paraffin blocks containing the tumor area.

Vaginal Müllerian papilloma in a 2-year-old child.

Papillomas of the lower genital tract are rare benign lesions, which cause vaginal bleeding in girls. We report a case in a 2-year-old girl. Few cases have been described in children and adolescents.