Serum endocan, asymmetric dimethylarginine and lipid profile in children with familial Mediterranean fever.

Background: Familial Mediterranean fever (FMF) is a chronic inflammatory disease, and it is thought that subclinical inflammation persists even when there are no attacks, eventually causing endothelial dysfunction (ED) and atherosclerosis. Limited data are available about serum endocan, asymmetric dimethylarginine (ADMA) and lipid profile in children with FMF, so we aimed to evaluate these markers in children with FMF during the attack-free period.

Methods: A total of 50 patients diagnosed with FMF and 50 age and sex-matched healthy children were recruited.