Publications by authors named "Wakayama A"

Objective: An intraosseous arteriovenous fistula (AVF) is a rare fistula with an intracranial shunted pouch. A case of an intraosseous AVF at the squamous part of the occipital bone with spontaneous occlusion of diploic venous drainage is described.

Case Presentation: The patient, a Japanese woman in her 80s, presented with headaches at the back of the head and a history of multiple unruptured cerebral aneurysms but no recent head trauma.

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Article Synopsis
  • The study investigates genetic factors related to meningiomas, a common type of brain tumor, specifically in a Japanese population, as previous research mainly focused on Europeans.
  • Researchers analyzed 401 meningioma patients and over 50,000 control participants, ultimately identifying over 8 million genetic variants but failing to find any significant variants associated with meningioma susceptibility.
  • This first genome-wide association study on meningiomas in East Asians aims to enrich future genetic research in this area, despite not yielding significant results.
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Neoplastic cerebral aneurysms (NCAs) are rare. This study reported a case of an NCA secondary to a poorly differentiated carcinoma of the parotid gland. An 84-year-old Japanese woman undergoing treatment for parotid gland cancer was admitted to our hospital with headache and progressive loss of consciousness.

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The indication for surgical intervention in spontaneous intracerebral hemorrhage remains controversial. Although many clinical trials have failed to demonstrate its efficacy over medical treatment, less invasive endoscopic treatment is expected to demonstrate its superiority. A novel endoscopic system for hematoma removal consisting of a 3.

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Purpose: No method to quantitatively evaluate stereopsis within the 15º visual field has been clinically established. We developed a program to measure paracentral stereopsis and evaluated its feasibility in visually normal participants.

Study Design: Experimental investigation METHODS: Ten visually normal volunteers with stereopsis of 60 arcseconds or better were included.

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Objective: The risk factors of procedural cerebral ischemia (CI) in ruptured middle cerebral artery (MCA) aneurysms are unclear. This study proposed the neck-branching angle (NBA), a simple quantitative indicator of the aneurysm neck and branch vessels, and analyzed its usefulness as a predictor of procedural CI in ruptured MCA aneurysms.

Methods: We retrospectively analyzed 128 patients with ruptured saccular MCA aneurysms who underwent surgical or endovascular treatment between January 2014 and June 2021.

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This study assessed the clinical performance of point-of-care testing (POCT) for quick cortisol assay (QCA) during adrenal vein sampling (AVS) using a newly invented portable quantitative assay instrument. An observational study was conducted prospectively at two centres in Japan. Forty-eight patients with primary aldosteronism considered for adrenalectomy were enrolled in this study and underwent AVS.

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Background: Amblyopia treatment by occluding the healthy eye is known to be effective during a sensitive critical period. This study aims to clarify the factors for the total occlusion time (TOT) required for the amblyopic eye to achieve a normal visual acuity (VA) level of 1.0 (0.

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Objective: Intracranial atherosclerosis disease (ICAD) is one of the most common causes of acute ischemic stroke. In endovascular treatment (EVT) for acute large vessel occlusion stroke-related ICAD, reocclusion of the recanalized artery due to in situ thrombosis is problematic. In this study, the safety and efficacy of prasugrel administration to avoid reocclusion of emergent EVT for ICAD was investigated.

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Purpose: To investigate the association between stereoacuity and suppression during occlusion therapy for patients with anisometropic amblyopia.

Design: Retrospective study.

Patients And Methods: This study included 19 patients with hyperopic anisometropic amblyopia who underwent occlusion therapy.

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Purpose: To investigate the treatment policy for amblyopia in Japan as of 2017 through a survey of multiple facilities and to compare the findings with those obtained by the Amblyopia Treatment Study (ATS) of the Pediatric Eye Disease Investigator Group.

Study Design: Questionnaire survey study.

Subjects And Methods: A questionnaire was sent to 181 facilities where patients with amblyopia are being treated.

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Purpose: To investigate the effects of orthoptic training for residual diplopia after blowout fracture (BOF) surgery.

Methods: We retrospectively reviewed the medical records of 14 (average age, 22.9 ± 13.

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Background: The efficacies of prism adaptation test (PAT) and monocular occlusion (MO) and their optimal test durations to detect the maximum angles of deviation at near and distance in eyes with intermittent exotropia (IXT) were assessed and compared.

Methods: We retrospectively reviewed the medical records of 72 patients with IXT. All the patients had undergone the initial strabismus surgery between April 2015 and October 2018 and had been preoperatively tested by both PAT and MO performed on different days for 30 and 60 min.

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Prcis: A difference between monocular sensitivities measured with and without occlusion was observed in glaucoma. Monocular sensitivity without occlusion could have been affected differently by binocular interaction due to the sensitivity disparity between both eyes.

Purpose: To investigate the influence of sensitivity disparity between both eyes on visual field results under binocular viewing in glaucoma.

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Background: The effect of intra-arterial infusion of fasudil hydrochloride in patients with post-traumatic cerebral vasospasm remains unclear. Here we report a case of intra-arterial infusion of fasudil hydrochloride for post-traumatic cerebral vasospasm.

Case Presentation: A 47-year-old man was transferred to our hospital with a fractured skull and traumatic subarachnoid hemorrhage.

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Purpose: Using a head-mounted perimeter imo that can measure monocular sensitivity with both eyes open, we investigated the difference between monocular sensitivities measured with and without occlusion of the fellow eye and if the difference was influenced by eccentricity.

Methods: Using the perimeter imo, monocular sensitivities with/without occlusion and binocular sensitivity were measured and compared. Three test conditions for monocular sensitivity without occlusion were: with/without a fusional fixation target, and a binocular random single eye test in which the target was randomly presented to either eye and the examinee was not aware of the tested eye.

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Background: Atraumatic acute subdural hematoma (ASDH) associated with moyamoya disease (MMD) is rare, and only a few studies have reported the bleeding origin. We present a case of atraumatic ASDH attributable to a transdural anastomosis that developed owing to the compensatory mechanisms involved in the pathogenesis of advanced MMD. This is the first case of life-threatening atraumatic ASDH associated with MMD in which the rupture point was clearly visualized using a 3-dimensional rotational reconstructed image.

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Purpose: To investigate the incidence rate and side effects of topical atropine sulfate and cyclopentolate hydrochloride for cycloplegia in children aged 15 years or under.

Methods: This prospective study had been conducted at 9 institutions between April 1, 2016 and March 31, 2017 in patients 15 years old or younger who received either atropine or cyclopentolate for refraction assessment. The investigation included patient's age, symptoms, and whether patients with side effects had any systemic diseases.

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Background/aim: We previously observed spotty hyperintense lesions in the region of the perforating arteries on peri-ictal diffusion-weighted imaging (DWI); however, no report has formally described these findings. The aim of this study was to investigate focal intensities on peri-ictal DWI, and to evaluate the clinical significance of these lesions.

Methods: We conducted a retrospective review of 677 consecutive patients with seizure who completed peri-ictal DWI within 24 h after seizure onset.

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Purpose: To examine the role of fusional convergence amplitude in postoperative phoria maintenance in childhood intermittent exotropia [X(T)].

Methods: The medical records of 29 children aged 15 years or younger (mean age, 10.8 ± 2.

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Obstructive sleep apnea syndrome (OSAS) is often associated with metabolic disorders such as obesity and type 2 diabetes and may contribute to cardiovascular events. A novel class of antidiabetic drugs, the sodium glucose cotransporter 2 inhibitors (SGLT2i) reduce body weight (BW), although there is limited data on their impact on OSAS. We therefore evaluated the effect of SGLT2i on OSAS in patients with type 2 diabetes.

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Background: Lymphovascular space involvement is reported to be an important risk factor in endometrial cancer. This study was conducted to evaluate the separate prognostic effects of lymphatic invasion and venous invasion on the outcomes of patients with endometrial cancer.

Methods: From 2006 to 2013, 189 histologically confirmed endometrial cancer patients were examined.

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Purpose: Patients with cervical cancer recurrence after concurrent chemoradiotherapy (CCRT) who are not candidates for surgical resection or salvage radiotherapy have a dismal prognosis. The predictive factors for the effects of chemotherapy and prognostic factors in these patients were analyzed.

Methods: We collected data for patients with recurrent cervical cancer who were primarily treated with CCRT between 2000 and 2013.

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•Secondary uterine sarcomas occur in < 1% of patients treated with CCRT.•Secondary uterine sarcomas can occur > 5 years from CCRT.•The median survival period from the secondary tumor occurrence was only 4 months.

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