Publications by authors named "Wakasa Shigemi"
Article Synopsis
- - The study aimed to compare how well brimonidine (BMD) and brinzolamide (BZM) are absorbed in the body when given together as a fixed-combination drug versus when they are administered separately to rabbits.
- - Researchers measured the concentration of both drugs in different parts of the eye and in the blood using advanced testing methods after administering the drugs in various formulations.
- - Results indicated that the fixed combination (FCBB) produced similar drug levels in the eye and bloodstream as the individual drugs, suggesting that the combined formulation may improve drug distribution, particularly in certain eye tissues, and that the timing of administration can affect absorption.
