Effect of medetomidine on tear flow measured by Schirmer tear test I in normal pigs.

Medetomidine, an α-adrenoceptor agonist, was reported to decrease tear flow in some species. However, there are no reports about the effect of medetomidine on tear flow in pigs. The purpose of this study was to elucidate it.

Sedative and physiological effects of brimonidine tartrate ophthalmic solution in healthy cats.

Objective: To determine the effects of brimonidine tartrate ophthalmic solution on sedation, heart rate (HR), respiratory frequency (f), rectal temperature (RT) and noninvasive mean arterial pressure (MAP) in healthy cats.

Study Design: Randomized, blinded crossover study, with 1 week washout between treatments.

Animals: Six healthy purpose-bred cats.