Clinical practice guideline on the prevention and management of neonatal extravasation injury: a before-and-after study design.

Background: Extravasation injury resulting from intravenous therapies delivered via peripheral intravenous catheters or umbilical and peripherally inserted central venous catheters is a common iatrogenic complication occurring in neonatal intensive care units. This study aimed to evaluate the effectiveness of an evidence-based clinical practice guideline in the prevention and management of neonatal extravasation injury by nurses.

Methods: A controlled before-and-after study was conducted in a neonatal unit.