Adjunctive modulation of wound healing during cataract surgery to promote survival of a previous trabeculectomy.

Background: Trabeculectomy is a surgical treatment for glaucoma to lower intraocular pressure with high success rates; however, it is often associated with an increased rate of cataract formation. Cataract can cause symptoms such as glare in bright conditions, foggy vision, and difficulty in driving at night. Cataract extraction surgery is highly successful in improving vision, but it comes at a cost of trabeculectomy failure, with a reported risk of 30% to 40%.

Laser peripheral iridoplasty for chronic angle closure.

Background: In at least a third of primary angle closure cases, appositional angle closure persists after laser peripheral iridotomy, and further intervention may be considered. Laser peripheral iridoplasty (LPIp) can be used in treating chronic angle closure when angle closure persists after laser peripheral iridotomy. Previous reviews have found insufficient data to determine its clinical effectiveness, compared to other interventions.

Artificial Intelligence Algorithms to Diagnose Glaucoma and Detect Glaucoma Progression: Translation to Clinical Practice.

Purpose: This concise review aims to explore the potential for the clinical implementation of artificial intelligence (AI) strategies for detecting glaucoma and monitoring glaucoma progression.

Methods: Nonsystematic literature review using the search combinations "Artificial Intelligence," "Deep Learning," "Machine Learning," "Neural Networks," "Bayesian Networks," "Glaucoma Diagnosis," and "Glaucoma Progression." Information on sensitivity and specificity regarding glaucoma diagnosis and progression analysis as well as methodological details were extracted.

Use of magnetic nanoparticles and oscillating magnetic field for non-viral gene transfer into mouse cornea.

Background: Inherited, iatrogenic, and metabolic corneal disease could be potentially treated by supplying a functional gene or changing the expression levels of specific genes. Viral-based gene therapy is efficient, but restricted by evoking immune responses and inflammation. This study aimed to transfect mouse cornea with a non-viral based (oscillating magnetofection) method.

Automated Registration of Multimodal Optic Disc Images: Clinical Assessment of Alignment Accuracy.

Purpose: To determine the accuracy of automated alignment algorithms for the registration of optic disc images obtained by 2 different modalities: fundus photography and scanning laser tomography.

Materials And Methods: Images obtained with the Heidelberg Retina Tomograph II and paired photographic optic disc images of 135 eyes were analyzed. Three state-of-the-art automated registration techniques Regional Mutual Information, rigid Feature Neighbourhood Mutual Information (FNMI), and nonrigid FNMI (NRFNMI) were used to align these image pairs.

Development and validation of a standardized tool for reporting retinal findings in abusive head trauma.

Purpose: To develop and validate a robust standardized reporting tool for describing retinal findings in children examined for suspected abusive head trauma.

Design: A prospective interobserver and intraobserver agreement study.

Method: An evidence-based assessment pro forma was developed, recording hemorrhages (location, layer, severity) and additional features.

Laser peripheral iridoplasty for angle-closure.

Background: Angle-closure glaucoma is a leading cause of irreversible blindness in the world. Treatment is aimed at opening the anterior chamber angle and lowering the IOP with medical and/or surgical treatment (e.g.

Oxane HD and retinal detachment surgery in routine clinical practice.

Background/aims: To assess the outcomes and complications of endotamponade with Oxane HD following retinal detachment repair.

Methods: Retrospective consecutive case series of inferior retinal detachment with Oxane HD endotamponade within a 3-year period.

Results: Case notes for 18 eyes of 18 patients were reviewed.

Laser peripheral iridoplasty for angle-closure.

Background: Angle-closure glaucoma is a leading cause of irreversible blindness in the world. Treatment is aimed at opening the anterior chamber angle and lowering the IOP with medical and/or surgical treatment (e.g.

Management of recurrent epistaxis in an anticoagulated patient by temporarily closing the nares with sutures.

We describe an unusual case of recurrent, refractory anterior epistaxis in an 86-year-old man with two mechanical heart valves who was on permanent warfarin therapy. His numerous episodes of epistaxis were incited by chronic nose-picking and strong nose-blowing, practices that he continued to engage in despite repeated medical advice to stop. Stopping his anticoagulation therapy was not considered as a management option because of an unacceptably high risk that this would lead to a thromboembolic event.