Publications by authors named "Wai Lun Tang"

Article Synopsis
  • * Analysis revealed that this plant contains effective compounds, particularly norstictic acid, stictic acid, and gyrophoric acid, that inhibit amyloid fibrillation and protect neuronal cells from damage caused by amyloid peptides.
  • * Findings suggest that herbal extracts and their active compounds could serve as potential neuroprotective and therapeutic agents for Alzheimer's, benefiting from their safe use in traditional medicine and food.
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Article Synopsis
  • The study aimed to see how the Prostate Health Index (PHI) affects clinical decisions for men with PSA levels between 4-10 ng/mL and normal digital rectal exams in Hong Kong public hospitals from 2016 to 2017.
  • Of 2828 patients followed for 2 years, 82% showed low PHI risk scores (under 35), leading 83% of those with elevated PSA to choose against biopsy, while higher PHI scores correlated with increased detection of high-grade prostate cancer.
  • The conclusion suggests that using PHI in clinical decisions helped reduce unnecessary biopsies and improved the detection of significant prostate cancer compared to traditional PSA methods.
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Purpose: 5-alpha reductase inhibitor (5ARI) reduces prostate-specific antigen (PSA) by half but its effect on prostate health index (phi) is unknown. This study aims to investigate this effect and to enable accurate interpretation of phi in men with elevated PSA and on 5ARI.

Methods: This is a prospective study evaluating the effect of finasteride on PSA, free PSA (fPSA), [ - 2]proPSA (p2PSA) and phi at 6 and 12 moths in men with PSA 4-20 ng/mL, no prior 5ARI use, and one negative prostate biopsy within 6 months before recruitment.

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Human sparganosis is a foodborne zoonosis endemic in Asia. We report a series of 9 histologically confirmed human sparganosis cases in Hong Kong, China. All parasites were retrospectively identified as Spirometra erinaceieuropaei.

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Bulbus Fritillariae is the most commonly used antitussive herb in China. Eleven species of Fritillaria are recorded as Bulbus Fritillariae in the Chinese Pharmacopoeia. Bulbus Fritillariae Cirrhosae is a group of six Fritillaria species with higher efficiency and lower toxicity derived mainly from wild sources.

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Two-phase solvent system plays crucial role in successful separation of organic compounds using counter-current chromatography (CCC). An interesting two-phase solvent system, composed of chloroform/ethyl acetate/methanol/water, is reported here, in which both phases contain sufficient organic solvents to balance their dissolving capacities. Adjusting the solvent system to get satisfactory partition coefficients (K values) for target compounds becomes relatively simple.

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Objective: Laparoscopic colectomy has been proved to be both technically and oncologically feasible. However, the approach has been criticized for its procedural complexity and long operative time as a result of the loss of tactile feedback and absence of depth perception. The advent of hand-access devices offered a potential solution to these problems.

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Despite advances in endoscopy and imaging, acute gastrointestinal (GI) bleeding of obscure origin in children presents a challenge to pediatric gastroenterologist. Bleeding Meckel's diverticulum (MD) commonly presents with acute episode of lower GI bleeding. A conventional diagnostic algorithm includes endoscopy, technetium 99m pertechnetate scintigraphy, angiography, and exploratory laparotomy.

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