Publications by authors named "Wai K Wong"

Article Synopsis
  • The study aimed to establish epidemiological cut-off values for the minimum inhibitory concentrations (MICs) of 10 antimicrobial agents against the bacteria Vibrio parahaemolyticus using standardized testing methods.
  • Eight laboratories conducted broth microdilution tests at two different temperatures (35°C and 28°C) to assess the effect of incubation temperature on MIC values, finding that many values were consistent across both temperatures.
  • The generated data will be submitted to the Clinical and Laboratory Standards Institute to help set international standards for interpreting antimicrobial susceptibility tests for this species.
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  • Esophagogastric junction outflow obstruction (EGJOO) is an esophageal disorder with a high integrated relaxation pressure, and while symptoms are usually self-limiting, this study investigates factors that affect symptom resolution.
  • A cohort study of 53 patients revealed that while dysphagia and atypical chest pain were common symptoms, obesity was a significant risk factor for persistent symptoms, with only 37.5% of obese patients seeing resolution compared to 87.2% of non-obese patients.
  • The study emphasizes that addressing obesity may be crucial for improving outcomes in patients with functional EGJOO, as it significantly impacts the likelihood of symptom resolution.
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Background: Only 80% of patients are satisfied with their outcomes post-TKA. Mounting attention has been paid to constitutional limb alignment and individualized alignment strategies in recent years. MacDessi et al.

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remains a significant foodborne pathogen globally with . Typhimurium presenting as a frequently occurring serovar. This study aimed to characterize 67 .

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Palm-vein has been widely used for biometric recognition due to its resistance to theft and forgery. However, with the emergence of adversarial attacks, most existing palm-vein recognition methods are vulnerable to adversarial image attacks, and to the best of our knowledge, there is still no study specifically focusing on palm-vein image attacks. In this paper, we propose an adversarial palm-vein image attack network that generates highly similar adversarial palm-vein images to the original samples, but with altered palm-identities.

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Background: The slit-mesh technique for laparoscopic groin hernia repair remains controversial. We present the largest cohort of patients to date that have undergone laparoscopic hernia repair with this technique and aim to evaluate the impact of both techniques on postoperative recurrence and other secondary outcomes.

Methods: A retrospective, single-institution cohort study of patients who underwent a laparoscopic groin hernia repair over a 5.

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Despite total knee arthroplasty (TKA) being the gold standard for end-stage knee osteoarthritis, 20% of patients remain dissatisfied. Robotic-assisted arthroplasty promises unparalleled control of the accuracy of bone cuts, implant positioning, control of gap balance, and resultant hip-knee-ankle (HKA) axis. Patients underwent clinical and radiological assessments, including knee CT scans and patient-reported outcome measures (PROMs), preoperatively.

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Background: Patients with hematological malignancy are at high risk of invasive fungal infections (IFIs). Diagnosis is challenging, which can lead to overtreatment. Reducing exposure to inappropriate antifungal prescribing is likely to improve patient safety, but modifying prescribing behavior is difficult.

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Introduction: Laparoscopic sleeve gastrectomy (LSG) is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE). The role of crural repair during LSG is still controversial. The preoperative laxity of the gastroesophageal junction (GEJ), graded by the Hill's classification, is more predictive for postoperative GERD and EE after LSG than the presence of a hiatal hernia seen on endoscopy.

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Background: Laparoscopic sleeve gastrectomy (SG) is a widely performed bariatric surgery, but it is associated with an increased risk of gastroesophageal reflux (GERD) in the long term. The addition of fundoplication to laparoscopic SG may improve lower oesophageal sphincter function and reduce postoperative GERD.

Objectives: This systematic review and meta-analysis aims to compare the efficacy and safety of SG plus fundoplication (SG + F) versus SG alone for the treatment of patients with severe obesity (≥35 kg/m).

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In the past decades, supervised cross-modal hashing methods have attracted considerable attentions due to their high searching efficiency on large-scale multimedia databases. Many of these methods leverage semantic correlations among heterogeneous modalities by constructing a similarity matrix or building a common semantic space with the collective matrix factorization method. However, the similarity matrix may sacrifice the scalability and cannot preserve more semantic information into hash codes in the existing methods.

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In Singapore, 10 captive lions tested positive for SARS-CoV-2 by real-time PCR. Genomic analyses of nanopore sequencing confirmed human-to-animal transmission of the SARS-CoV-2 Delta variant. Viral genomes from the lions and zookeeper shared a unique spike protein substitution, S:A1016V.

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We detected African swine fever virus (ASFV) from a wild boar in Singapore. In <72 hours, we confirmed and reported ASFV p72 genotype II, CD2v serogroup 8, and IGR-II variant by using a combination of real-time PCR and whole-genome sequencing. Continued biosurveillance will be needed to monitor ASFV in Singapore.

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Background: Hope can affect the thinking habits, emotional regulations, and behaviors of individuals. Hope is considered as a positive trait by clinicians, who often assess the level of hope in psychological evaluations. Previous measurements of hope were largely based on self-reported questionnaires leading to the problem of subjectivity.

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As a branch of transfer learning, domain adaptation leverages useful knowledge from a source domain to a target domain for solving target tasks. Most of the existing domain adaptation methods focus on how to diminish the conditional distribution shift and learn invariant features between different domains. However, two important factors are overlooked by most existing methods: 1) the transferred features should be not only domain invariant but also discriminative and correlated, and 2) negative transfer should be avoided as much as possible for the target tasks.

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Unlabelled: WHAT IS KNOWN ON THE SUBJECT?: Family-involved interventions can result in better outcomes than traditional mental health care for both service users and their families. Nurses' attitudes towards family involvement can affect family participation in care. Earlier studies on psychiatric nurses' attitudes towards family involvement in care report ambiguous findings.

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Background: Constipation is a functional gastrointestinal disorder that presents with signs and symptoms, which are typically assessed subjectively. Various measurement scales, such as the Constipation Assessment Scale (CAS), are commonly used to evaluate constipation among the general population. However, the instruments should be culturally and contextually relevant in adult psychiatric patients to generate valid and reliable evidence.

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Background: Insights into behaviours relevant to the transmission of infections are extremely valuable for epidemiological investigations. Healthcare worker (HCW) mobility and patient contacts within the hospital can contribute to nosocomial outbreaks, yet data on these behaviours are often limited.

Methods: Using electronic medical records and door access logs from a London teaching hospital during the COVID-19 pandemic, we derive indicators for HCW mobility and patient contacts at an aggregate level.

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Diabetic retinopathy (DR), one of the most common and serious complications of diabetes, has become one of the main blindness diseases. The retinal vasculature is the only part of the human circulatory system that allows direct noninvasive visualization of the body's microvasculature, which provides the opportunity to detect the structural and functional changes before DR becomes unable to intervene. For decades, as the fundamental step in computer-assisted analysis of retinopathy, retinal vascular extraction methods have been largely developed.

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Article Synopsis
  • Idiopathic normal pressure hydrocephalus (iNPH) is a progressive condition that is often underdiagnosed, and early treatment is crucial for improving patients' outcomes and quality of life.
  • Researchers utilized natural language processing (NLP) to analyze electronic health records of patients to gather information about iNPH, with plans to create AI tools for early detection.
  • A total of 293 eligible patients were identified, mainly older men (average age 75), and the study successfully extracted relevant clinical features, finding common symptoms related to mobility, cognitive impairment, and balance issues.
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Attitudes toward aggression is a controversial phenomenon in psychiatry. This study examined and compared attitudes toward patient aggression in psychiatric hospitals from the perspectives of nurses, patients and informal caregivers and identified factors associated to these attitudes. A total of 2,424 participants completed a self-reported instrument regarding attitudes toward aggression (12-items Perception of Aggression Scale; POAS-S).

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Article Synopsis
  • As healthcare organizations increasingly adopt electronic health record (EHR) systems, the effective use of unstructured data for service improvement and clinical research becomes a significant challenge.
  • The CogStack platform, implemented at University College London Hospitals, utilizes natural language processing and data management tools to extract and analyze data from various sources, enhancing research capabilities.
  • Since its deployment, CogStack has processed over 30 million records, providing valuable insights that have contributed to several clinical research initiatives at the hospital.
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Objective: To present a case of giant cholesteatoma and review of the contemporary literature.

Patients: A 61-year-old male presented with foul-smelling discharge from his right ear in the setting of a previous canal wall down mastoidectomy. Otomicroscopy demonstrated a mastoid cavity filled with infected keratinous debris.

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Synopsis of recent research by authors named "Wai K Wong"

  • - Wai K Wong's recent research focuses on diverse fields including public health, surgical techniques, and biometrics, addressing significant issues such as antimicrobial resistance, adversarial attacks in biometric recognition, and surgical outcomes in hernia repairs and obesity treatments.
  • - His studies utilize extensive cohort analyses, systematic reviews, and innovative methodologies, such as robotic-assisted surgery and machine learning applications in transfusion medicine, demonstrating a commitment to improving clinical practices and patient outcomes.
  • - Wong has also explored emerging infectious diseases and zoonotic transmission, as evident in his work on SARS-CoV-2 transmission to lions, indicating a broader interest in the intersection of human health and environmental factors.