Publications by authors named "Wai Chung Wong"

Article Synopsis
  • Ollier's disease is a rare, nonhereditary condition caused by mutations in IDH1 and IDH2 genes, usually showing symptoms in early life and characterized by multiple enchondromas on one side of the body.
  • Diagnosis involves clinical evaluations and imaging techniques like radiology, and it's crucial to monitor the condition due to the risk of enchondromas turning into malignant chondrosarcomas.
  • The case report focuses on a 25-year-old male with swellings in specific areas, highlighting the importance of bone scans and plain X-rays in managing his multiple enchondromas.
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An 18-year-old male with multiple endocrine neoplasm type 1 (MEN1) syndrome presented with hyperparathyroidism. Parathyroidectomy was performed. Patient complained of bone pain afterwards, multiple imaging modalities revealed features of osteitis fibrosa cystica and biochemical profile showed features of hungry bone syndrome.

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Objectives: The study aimed to evaluate the frequency of incidental suspicious lesions detected by flourine-18 fluorodeoxyglucose PET/computed tomography ( 18 F-FDG PET/CT) scans done for staging or restaging in adult cancer patients. We further determined the detection rate of synchronous and metachronous malignancies in these suspicious lesions after further investigations.

Materials And Methods: This retrospective analysis evaluated the consecutive patients with 18 F-FDG PET/CT scans done in Queen Elizabeth Hospital (QEH), Hong Kong between July 2021 and June 2022.

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Purpose: We aimed to investigate the incidence and clinical significance of incidental focal nasopharyngeal uptake on [F]FDG PET/CT and to evaluate the diagnostic performance of various metabolic parameters to differentiate between benign and malignant nasopharyngeal lesions.

Methods: A total of 63 consecutive patients with incidental focal nasopharyngeal uptake on [F]FDG PET/CT and subsequent nasopharyngeal biopsy were retrospectively enrolled. In addition, baseline pretherapeutic [F]FDG PET/CT images of 59 patients with newly diagnosed pathologically proven nasopharyngeal carcinoma (NPC) were reviewed.

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There is a critical need for better malaria rapid diagnostic tests to discriminate Plasmodium falciparum and Plasmodium vivax infection given the recent observation of HRP2 deletions in P. falciparum parasites. We previously identified a DNA aptamer, 2008s, that targets P.

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Innovative nanomaterials offer significant potential for diagnosis of severe diseases of the developing world such as malaria. Small sized silver nanoclusters have shown promise for diagnostics due to their intense fluorescence emission and photo-stabilities. Here, double-stranded DNA-scaffolded silver nanoclusters (AgNCs-dsDNA) were prepared to detect the established malaria biomarker, Plasmodium falciparum lactate dehydrogenase (PfLDH).

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Omental ectopic pregnancy is a rare form of ectopic pregnancy. Presented here is a case primary omental ectopic pregnancy according to Studdiford's criteria. This patient presented with epigastric pain and anemia without vaginal bleeding, lower abdominal or pelvic pain.

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