PHARMACOKINETIC, PHARMACODYNAMIC, AND TOXICOLOGY STUDY OF ROBENACOXIB IN RAINBOW TROUT ().

Postoperative antinociception control in fish is currently suboptimal, as commonly used antiinflammatory drugs last for only a few hours at tested temperatures. Therefore, long-acting anti-inflammatory drugs, such as robenacoxib, could improve the welfare of fish. The pharmacokinetics, duration of antinociceptive action, and potential adverse effects of robenacoxib were evaluated through two prospective randomized blinded trials in rainbow trout ().

A PRELIMINARY STUDY OF INTRINSIC AND EXTRINSIC FACTORS INFLUENCING INTRAOCULAR PRESSURE IN BROOK TROUT ().

Reference intervals of intraocular pressure (IOP) are poorly described in piscine species as the factors that may influence it. Rebound tonometry was used to measure IOP in 28 adult brook trout () anesthetized in a buffered solution of 60 mg/L tricaine methanesulfonate ( = 16) or restrained with electronarcosis ( = 12) at 16 mA. There was no significant effect of the eye side, sex, fish origin, and body weight, but IOP values were significantly higher with electronarcosis (mean ± SD: 16.

A CLUSTER OF CASES OF THYROID HYPERPLASIA IN AQUARIUM-HOUSED TROPICAL MARINE TELEOSTS FOLLOWING A CHANGE OF SALT MIX BRAND.

Follicular thyroid hyperplasia was diagnosed in nine out of 32 (28%) marine tropical teleosts housed in a public aquarium over a 9.5-mo period. These proliferative lesions were considered to be the cause of death in five of these fish.