Valorization of shrimp processing waste-derived chitosan into anti-inflammatory chitosan-oligosaccharides (CHOS).

Bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using a Bacillus chitosanase, BsCsn46A, was investigated, including food-grade approaches. After 48 h of enzymatic reaction, most of the final products were dimers and trimers. None of the CHOS products showed toxicity to human fibroblasts.