Lipase-copper complex/chitosan microspheres; loaded with attapulgite used for the treatment of E. coli-induced diarrhea.

Diarrhea is a globally major problem especially Escherichia coli induced diarrhea becoming fatal nowadays in developing countries. Colon-targeted chitosan microspheres (Ms) comprising of lipase‑zinc and lipase‑copper complexes were prepared, loaded with Attapulgite (Cts-Li-Zn-ATG/Ms and Cts-Li-Cu-ATG/Ms) for the treatment of bacterial diarrhea. Thin layer chromatography (TLC) and Fourier-transform infrared spectroscopy (FTIR) studies were used for confirmation of proposed lipase-metal complexes.

Fluorescence switch based on NIR-emitting carbon dots revealing high selectivity in the rapid response and bioimaging of oxytetracycline.

The abuse of antibiotics has led to serious environmental pollution and the emergence of drug-resistant bacteria surpassing the replacement rate of antibiotics. Herein, near-infrared fluorescent carbon dots (NIR-CDs) were developed to meet the requirements for oxytetracycline (OTC) detection in food and water samples (milk, honey, and lake water) with a detection limit of 0.112 μM.

Zero Thermal Quenching Phenomenon of Green Emitting Carbon Dots with High Biocompatibility and Stable Multicolor Biological Imaging in a Hot Environment.

Carbon dots are emerging fluorescent nanomaterials with unique physical and chemical properties and a wide range of applications. Herein, we have designed and successfully synthesized thermally stable green emissive nitrogen-doped carbon dots (NCDs) with a photoluminescent quantum yield of 11.32% through facile solvent-free carbonization.

A review of the growing trend towards heteroatoms-doped carbon dots based on dopamine acting as a hybrid agent and detected analyte.

Dopamine (DA) is a biomolecule that plays a critical part in the functioning of our brains by promoting motivation, maintaining focus, and altering mood. Excessive or low-level concentrations of DA in the human brain led to a dangerous neurological disorder. It is significantly important to trace the precise amount of DA to prevent such risky brain disease.

CS8 improves phytoremediation potential of for tannery solid waste polluted soil.

Microbes have shown potential for the bioremediation of tannery waste polluted soil. During our previous study, it was observed that heavy metal resistant CS8 augmented growth and phytoremediation capability of an ornamental plant. Objective of the present research work was to evaluate the capability of CS8 assisted plants for the phytoremediation of tannery solid waste (TSW) polluted soil.

Unlocking infodemics and mysteries in COVID-19 vaccine hesitancy: Nexus of conspiracy beliefs, digital informational support, psychological Well-being, and religious fatalism.

Guarding against an anti-science camouflage within infodemics is paramount for sustaining the global vaccination drive. Vaccine hesitancy remains a growing concern and a significant threat to public health, especially in developing countries. Infodemics, conspiracy beliefs and religious fatalism primarily fuel vaccine hesitancy.

High biocompatible nitrogen and sulfur Co-doped carbon dots for Hg(II) detection and their long-term biological stability in living cells.

Fluorescent carbon dots have been highly reported nanomaterials in recent times because of their excellent physio-chemical properties and various field of applications. Herein, a one-step hydrothermal approach was used to synthesize high biocompatible nitrogen and sulfur co-doped carbon dots, and examined their chemical sensing (Hg) and biological imaging properties. The N,S-CDs exhibited blue light, demonstrating a high quantum yield of up to 44.

Semiconductor photocatalysts: A critical review highlighting the various strategies to boost the photocatalytic performances for diverse applications.

The photocatalytic technology illustrates an eco-friendly and sustainable route to overcome environmental and energy issues. The successful construction of a photocatalyst depends on four key elements: light absorption ability, the density of active sites, redox capacity, and photoinduced electron-hole recombination rate. Sincemost of intrinsic semiconductor photocatalysts cannot meet all these requirements, they are often modified to boost their photocatalytic properties.

Concomitant Effect of Quercetin and Its Copper Complex in the Development of Sustained-Release Nanoparticles of Polycaprolactone, Used for the Treatment of Skin Infection.

The study aimed to improve the treatment of impetigo with naturally occurring quercetin and its copper-quercetin (Cu-Q) complex by preparing sustained-release (SR) nanoparticles of polycaprolactone (PCL). The solvent evaporation method was used for the copper-quercetin (Cu-Q) complex formation, and their PCL nanoparticles (PCL-NPs, Q-PCL-NPs, and Cu-Q-PCL-NPs) were prepared by the high-pressure homogenization method. Synthesis of nanoparticles was confirmed by their physicochemical and antibacterial properties of quercetin against Gram-positive as well as Gram-negative bacteria.

Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis.

Atherosclerosis and its complications are major causes of cardiovascular morbidity and death. Apart from risk factors such as hypercholesterolemia and inflammation, the causal molecular mechanisms are unknown. One proposed causal mechanism involves elevated levels of reactive oxygen species (ROS).

Prevalence and correlates of COVID-19 vaccine hesitancy among the elderly in Qatar: A cross-sectional study.

Older individuals are more vulnerable to severe coronavirus disease 2019 and medical complications. Vaccination stands as an efficient and safe vanguard against infection. However, negative attitudes and perceptions pertaining to available vaccines might hinder community inoculation.

Sr and Zr Co-Doped CaCuTiO Ceramics with Improved Dielectric Properties.

The dielectric constant of CCTO materials can be as high as 10, which makes it suitable for use in electronic devices but the high dielectric loss limits its application. In this paper, a series of Sr and Zr co-doped CCTO ceramics having the formula CaSrCuTiZrO ( = 0.1, 0.

Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric.

In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric with alkali leads to the formation of active sites for surface modification, followed by dip coating with silver nanoparticles and chitosan. The surface was chlorinated in the next step to transform amide (N-H) groups in chitosan into N-halamine (N-Cl).

Fluorescent Carbon Dots an Effective Nano-Thermometer in Vitro Applications.

Fluorescent sensing of temperature in nanoscale regions has many advantages and applications in the biological field. Herein, blue emitting carbon dots (CDs) are designed and successfully developed using a one step hydrothermal method. As synthesized CDs exhibit temperature dependent photoluminescent (PL) intensity and PL decay lifetime over the physiological temperature ranging from room temperature (RT) to 70 °C.

Supramolecular lipid nanoparticles as delivery carriers for non-invasive cancer theranostics.

Nanotheranostics is an emerging frontier of personalized medicine research particularly for cancer, which is the second leading cause of death. Supramolecular aspects in theranostics are quite allured to achieve more regulation and controlled features. Supramolecular nanotheranostics architecture is focused on engineering of modular supramolecular assemblies benefitting from their mutable and stimuli-responsive properties which confer an ultimate potential for the fabrication of unified innovative nanomedicines with controlled features.

Liquiritoside Alleviated Pb Induced Stress in subsp. : Modulations in Glucosinolate Content and Some Physiochemical Attributes.

Current research was conducted to explore the effects of liquiritoside on the growth and physiochemical features of Chinese flowering cabbage ( subsp. ) under lead (Pb) stress. Lead stressed plants exhibited decreased growth parameters, chlorophyll, and carotenoid contents.

Role of magnesium oxide nanoparticles in the mitigation of lead-induced stress in : modulation in polyamines and antioxidant enzymes.

During the current study, the effects of magnesium oxide nanoparticles (5 mmol/L) were observed on the growth and mineral nutrients of under lead (Pb) stress. The results demonstrated that Pb stress decreased the growth and photosynthetic rate of plants. Furthermore, Pb stressed plants showed decreased uptake of mineral nutrients including Zn, Na, Fe, K, Ca, Mg, K, and Cu.

Silicon assisted ameliorative effects of iron nanoparticles against cadmium stress: Attaining new equilibrium among physiochemical parameters, antioxidative machinery, and osmoregulators of Phaseolus lunatus.

Currently, producing safe agricultural commodities from the crop plants cultivated in the soil with increasing heavy metal toxicity is a gigantic challenge in front of researchers. Heavy metals are absorbed and translocated in the crop plants and then transferred to every downstream consumer of the food chain, including humans, causing serious disorders and ailments. The current research presents a combined schematic application of iron nanoparticles (Fe-NPs) and/or silicon (Si), to mitigate cadmium (Cd) stress in Lima bean (Phaseolus lunatus).

Metabolomic and Pharmacologic Insights of Aerial and Underground Parts of Fisch. ex DC. for Maximum Utilization of Medicinal Resources.

The roots of spp. have been utilized in Traditional Chinese medicine (TCM) for thousands of years. Non-traditional (aerial) parts constitute a large portion of the biomass of Glycyrrhiza plants and are mostly discarded after harvesting the roots and rhizomes.

Water-soluble green-emitting carbon nanodots with enhanced thermal stability for biological applications.

High stability and water solubility of fluorescent nanomaterials are considered key factors to evaluate their feasibility for fundamental applications. Herein, water-soluble and thermally stable, green-emitting carbon nanodots (CNDs) have been synthesized via a facile hydrothermal method with an average size of 1.9 nm.