Effective Radiation Therapy for Isolated Apical Pulmonary Amyloidoma: A Case Report and Treatment Insight.

BACKGROUND Amyloidosis refers to an assortment of diseases characterized by the accumulation and deposition of misfolded proteins in the extracellular matrix of tissues and organs. It may present systemically, affecting multiple organs, or locally by affecting a single organ. When the lungs or mediastinal structures are involved, the term pulmonary amyloid is used.

Bicarbonate and Serum Lab Markers as Predictors of Mortality in the Trauma Patient.

Introduction: Severe trauma-induced blood loss can lead to metabolic acidosis, shock, and death. Identification of abnormalities in the bicarbonate and serum markers may be seen before frank changes in vital signs in the hemorrhaging trauma patient, allowing for earlier lifesaving interventions. In this study the author aimed to evaluate the usefulness of serum bicarbonate and other lab markers as predictors of mortality in trauma patients within 30 days after injury.

Biomechanics of a laterally placed sacroiliac joint fusion device supplemental to S2 alar-iliac fixation in a long-segment adult spinal deformity construct: a cadaveric study of stability and strain distribution.

Objective: S2 alar-iliac (S2AI) screw fixation effectively enhances stability in long-segment constructs. Although S2AI fixation provides a single transarticular sacroiliac joint fixation (SIJF) point, additional fixation points may provide greater stability and attenuate screw and rod strain. The objectives of this study were to evaluate changes in stability and pedicle screw and rod strain with extended distal S2AI fixation and with supplemental bilateral integration of two sacroiliac joint fusion devices implanted using a traditional minimally invasive surgical approach.

Biomechanical effects of a novel posteriorly placed sacroiliac joint fusion device integrated with traditional lumbopelvic long-construct instrumentation.

Objective: S2-alar-iliac (S2AI) screw fixation effectively ensures stability and enhances fusion in long-segment constructs. Nevertheless, pelvic fixation is associated with a high rate of mechanical failure. Because of the transarticular nature of the S2AI screw, adding a second point of fixation may provide additional stability and attenuate strains.

Latino parent involvement and associations with home literacy and oral reading fluency.

Objective: Grounded in Hoover-Dempsey and Sandler's theoretical model of parents' motivations for involvement in their children's education, the aim of this study was to examine the associations between Latino parents' perceptions of involvement and the home literacy environment, as well as children's oral reading fluency (ORF). We further considered salient contextual factors (i.e.

Valine and isoleucine requirement of 20- to 45-kilogram pigs.

Three experiments were conducted to determine the Val and Ile requirements in low-CP, corn-soybean meal (C-SBM) AA-supplemented diets for 20- to 45-kg pigs. All experiments were conducted for 26 to 27 d with purebred or crossbred barrows and gilts, which were blocked by initial BW. Treatments were replicated with 5 or 6 pens of 3 or 4 pigs per pen.

Technical note: Effect of determining baseline plasma urea nitrogen concentrations on subsequent posttreatment plasma urea nitrogen concentrations in 20- to 50-kilogram pigs.

Plasma urea N (PUN) has been used as an indicator of AA requirements and efficiency of AA utilization in swine. However, PUN concentrations vary among a population of pigs, even a population with a close range of BW and fed the same diet. Thus, pretreatment or baseline PUN concentrations are used as a covariate to reduce variation of posttreatment PUN.

Maximizing the use of supplemental amino acids in corn-soybean meal diets for 20- to 45-kilogram pigs.

Four experiments were conducted to determine the Lys requirement, the maximum amount of supplemental Lys that does not decrease growth performance, and to determine the order of limiting AA beyond Lys, Thr, Trp, and Met in a corn-soybean meal diet for 20- to 45-kg pigs. All experiments were conducted for 27 to 28 d with purebred or crossbred barrows and gilts, which were blocked by initial BW. Treatments were replicated with 4 to 6 pens of 4 to 6 pigs per pen.

Additivity of effects from dietary copper and zinc on growth performance and fecal microbiota of pigs after weaning.

Four experiments were conducted to determine the interactive effects of pharmacological amounts of Zn from ZnO and Cu from organic (Cu-AA complex; Cu-AA) or inorganic (CuSO(4)) sources on growth performance of weanling pigs. The Cu was fed for 4 (Exp. 1) or 6 (Exp.

Uric acid, urea, and ammonia concentrations in serum and uric acid concentration in excreta as indicators of amino acid utilization in diets for broilers.

Five experiments were conducted to determine if serum uric acid, serum urea N (SUN), serum ammonia, and the uric acid content of the excreta (UAE) could be used to determine the efficacy of amino acid (AA) utilization in diets for broilers. All experiments were conducted with Ross x Ross 308 or 708 broilers from 0 to 14 or 0 to 18 d posthatching in brooder batteries. Treatments had 6 or 7 replications with at least 6 broilers per replicate pen.

Effect of incremental levels of L-lysine and determination of the limiting amino acids in low crude protein corn-soybean meal diets for broilers.

Research was conducted to determine the level of l-Lys that can be included in corn-soybean meal (C-SBM) diets for broilers before an amino acid (AA) beyond Met, Lys, Thr, or Gly becoming limiting and to determine the order of limiting AA in low CP C-SBM diets. All experiments were conducted with Ross 708 broilers (0 to 18 d of age) in brooder batteries. Treatments contained 7 or 8 replicates with 6 birds per replicate.

Naris occlusion alters transductory protein immunoreactivity in olfactory epithelium.

We have recently shown that unilateral naris occlusion (UNO) causes an increase in olfactory marker protein (OMP) immunoreactivity (IR) in mouse olfactory sensory neurons (OSN) from the occluded side of the nasal cavity and a decrease in OMP-IR on the non-occluded side, relative to controls. Given OMP's demonstrated role in olfactory modulation, these OMP-IR changes have been interpreted as a compensatory response by OSNs to odor deprivation on the occluded side and to supernormal exposure to odor on the non-occluded side of the nasal cavity. In the current study, we examined the developmental timing and the regional distribution of this process throughout the nasal cavity using immunocytochemistry.

Naris occlusion alters olfactory marker protein immunoreactivity in olfactory epithelium.

Though its function remains obscure, olfactory marker protein (OMP) has been implicated in olfactory transduction and the enhancement of neurogenesis within olfactory epithelium. Here we show, using Western blot analysis and immunocytochemistry, that unilateral naris occlusion (UNO) on postnatal day 1 alters OMP immunoreactivity (IR) differentially on the occluded and non-occluded sides of the nasal cavity in 18, 24 and 70-day-old mice. Compared to untreated animals, UNO-treated animals had a decrease in OMP-IR in olfactory receptor neurons on the non-occluded side and an increase in OMP-IR in olfactory receptor neurons on the occluded side of the nasal cavity.

Etiology of long-term failures of lumbar spine surgery.

Background Context: Patients who do not improve after lumbar surgery may be given the nonspecific label of "failed back surgery syndrome (FBSS)." Since 1981, there has not been a quantitative assessment of the etiologies of FBSS despite major improvements in surgical techniques and diagnostic testing.

Purpose: To define the causes of FBSS seen in a referral-based spine center.

Ossification of the ligamentum flavum as a cause of myelopathy in North America: report of three cases.

Myelopathy caused by ossification of the ligamentum flavum is a rare condition in North America. The authors describe three patients whose myelopathy was attributed to posterior cord compression warranting laminectomy to decompress the cervical spine (in one patient) and the thoracic spine (in two patients). The spinal computed tomographic scan (especially after myelography) can be instrumental in guiding the management of this condition.

'Clearing' cervical spine injuries in polytrauma patients: is it really safe to remove the collar?

Polytrauma patients are at increased risk for occult cervical spine injuries. Those unable to provide clinical clues to injury either remain in hard collars until they are able to cooperate with the physical examination or are deemed "clear of cervical injury" if the emergency room screening radiographs are without obvious bony abnormality. Cervical immobilization for a lengthy period of time is not without morbidity.

A new look at the promoter of the human monoamine oxidase A gene: mapping transcription initiation sites and capacity to drive luciferase expression.

Monoamine oxidase (MAO) A (EC 1.4.3.

Further studies of the role of opioid receptors in the nigra in the morphine withdrawal syndrome.

Bilateral injection of naloxone (3.0-30.0 nmol) into the substantia nigra of morphine-dependent rats produced a withdrawal syndrome consisting of wet-dog shakes, teeth chattering, irritability to touch, diarrhea and hypothermia.

Immunological uniqueness of human monoamine oxidases A and B: new evidence from studies with monoclonal antibodies to human monoamine oxidase A.

Monoamine oxidase (EC 1.4.3.