A statistical approach was implemented in the study of histologic characteristics from ex vivo basal cell carcinomas, based on the properties of backscattered acoustic waves, for the purpose of evaluating the method as a diagnostic tool. The study was developed using an ultrasound biomicroscope working at a frequency of 45 MHz. The parameters examined were signal-to-noise ratio (SNR), and shape parameters from the Weibull (b(W)) and generalized gamma (c(GG) and υ(GG)) probability density functions.
View Article and Find Full Text PDFUltrasound breast images have been used to improve diagnostics and decrease the number of unneeded biopsies. Malignant breast tumors tend to present irregular and blurred contours while benign ones are usually round, smooth and well-defined. Accordingly, investigating the tumor contour may help in establishing diagnosis.
View Article and Find Full Text PDFThis work aims at investigating seven morphological parameters in distinguishing malignant and benign breast tumors on ultrasound images. Linear discriminant analysis was applied to sets of up to five parameters and then the performances were assessed using the area Az (+/- standard error) under the ROC curve, accuracy (Ac), sensitivity (Se), specificity (Sp), positive predictive value and negative predictive value. The most relevant individual parameters were the normalized residual value (nrv) and overlap ratio (RS), both calculated from the convex polygon technique, and the circularity (C).
View Article and Find Full Text PDFComput Methods Programs Biomed
September 2007
Objective: This work develops a discrete-event computer simulation model for the analysis of a mammography clinic performance.
Material And Methods: Two mammography clinic computer simulation models were developed, based on an existing public sector clinic of the Brazilian Cancer Institute, located in Rio de Janeiro city, Brazil. Two clinics in a total of seven configurations (number of equipment units and working personnel) were studied.