Human leukocyte antigen HLADRB1 determinants susceptibility to gastroesophageal reflux disease.

Background: - Gastroesophageal reflux disease (GERD) is characterized by diverse symptoms. There is an evidence for a genetic component to GERD as supported by familial aggregation of this disease.

Objective: - To investigate whether certain human leucocyte antigen genes HLA-DRB1 are associated with GERD.

Frequency of antisperm antibodies in infertile women.

Background: Infertility is one of the common problems seen in couples of reproductive age. Presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. This study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins (IgG, IgM and IgA).