Modulatory effects of catechin hydrate on benzo[a]pyrene-induced nephrotoxicity in adult male albino rats.

Benzo [a] pyrene (B[a]P) is a potent mutagen and carcinogen, considered one of the commonest concomitants in the environment. The study aimed to evaluate the effect of catechin hydrate on benzo pyrene-induced kidney toxicity. Thirty-six adult male albino rats were divided into six groups: group I untreated control, group II received 10 mL/kg of corn oil (solvent of benzo [a] pyrene) twice a week, group III received 1 mL/kg 0.

Effects of catechin hydrate in benzo[]pyrene-induced lung toxicity: roles of oxidative stress, apoptosis, and DNA damage.

The major sources for human exposure to Benzo [] pyrene (B[a]P) are contaminated food, water, and inhalation of polycyclic aromatic hydrocarbon. B[]P is a well-known human genotoxic carcinogen (IARC Group 1). It has a tumorigenic potential in virtually all experimental animal model systems.