Loss of Purkinje cell-associated benzodiazepine receptors spares a high affinity subpopulation: a study with pcd mutant mice.

In order to identify the relative number of benzodiazepine (BZ) receptors in Purkinje and granule cells, the Purkinje cell degeneration (pcd) mutant mouse was used at different ages. In these mice, Purkinje cells have degenerated almost completely by 45-50 days of age. Granule cell loss occurs only later, and is most severe between 180 and 300 days.

Absence of variation in facteur thymique sérique activity in moderately and severely malnourished Senegalese children.

Facteur thymique sérique activity was evaluated in relation to different types of malnutrition in Senegalese children aged 5 to 42 months. They were classified in four groups: controls, moderate malnutrition, marasmus, and kwashiorkor, according to anthropometric measurements and clinical examination. The two latter groups were characterized by very depressed levels of total protein, album in, transferrin and prealbumin, and by high cortisol concentrations.

The effect of lateral visual fixation on response latency to verbal and spatial questions.

The results of several studies have suggested a relationship between lateral eye movements and contralateral hemispheric activation or ipsilateral inhibition. The present study investigated the effects of lateral and central eye fixation on response latency to verbal and spatial questions. Response latencies for verbal questions were significantly longer when subjects fixated to the left or centrally, as compared to the right.

Effect of early postnatal under- and overnutrition on the development of IgA plasma cells in mouse gut.

Development of gut IgA plasma cells was studied in early postnatal under- and overnutrition. Female mice were allowed to suckle in litters of 4, 9 or 20 pups to produce a state of obesity (litter of 4) or protein-energy malnutrition (litters of 20). Litters of nine were considered as control groups.

Influence of vascular and lumen flow on sodium movements across anuran intestine in vitro.

There is a positive linear relation between the vascular flow rate and the magnitudes of the unidirectional fluxes of Na in either direction in the steady state across the small intestine of the frog. Both unidirectional Na fluxes increase to the same extent with an increase in vascular flow so there is no apparent effect of flow on net Na movement. Raising the vascular flow rate in individual experiments increases the lumen-blood Na flux proportionately, but reducing the flow from an initially high value reduces the lumen-blood flux only slowly at first then more rapidly.

Sodium movements across the vascularly perfused anuran small intestine and colon.

Values of unidirectional Na fluxes measured across the vascularly perfused small intestine of three anuran species are higher than those found in other preparations in vitro. In Rana ridibunda and R. pipiens no net movement of Na across the small intestine can be detected.

Ostertagiosis in captive bison in New York State: report of nine cases.

Type II ostertagiosis was found at necropsy in 9 American bison (Bison bison) from 3 farms in New York. Clinical signs included severe diarrhea, emaciation, unthrifty coats, anemia, and weakness. In severely affected animals, the macroscopic abomasal changes consisted of irregular thickening and edema of the mucosa, resulting in a pebbly or morocco-leather appearance.

Skin changes and diseases associated with pregnancy.

During the gestational period, the skin is among the many organs undergoing changes. Various endocrine changes occurring in pregnancy are thought to give rise to certain skin changes such as pigmentary alterations, abnormalities in hair growth, vascular anomalies, and striae. Also, there are several skin diseases unique to the pregnant woman.

Mammalian host- and fluid-mediated mutagenicity assays of captan and streptozotocin in Salmonella typhimurium.

The mutagenicity of captan and of streptozotocin was tested in vivo by reversion of hisG46 base-pair substitution histidine auxotrophs of Salmonella typhimurium in the peritoneal cavity or in blood, plasma or urine of rats or mice. Genetic response was determined by the frequency of revertants (quantitative test) or by the number of revertants per plate (semiquantitative test). In quantitative HMA captan gave negative results following 3 hourly 500 mg/kg s.

Prevalence of Dirofilaria immitis in a stray dog population in western New York.

In a survey in 1973 undertaken to determine the prevalence of Dirofilaria immitis in 100 dogs from a public pound in western New York, 2 dogs were found to be positive. Microfilariae of Dipetalonema sp were not present. Hearts and pulmonary blood vessels were dissected for adult worms, and blood samples were examined for microfilariae, using a modified Knott technique.