J Clin Psychopharmacol
December 2024
Following a decades-long decline in psychedelic research resulting from social, political, and legislative factors, there has been greatly renewed interest in these compounds' ability to treat psychiatric disorders. Classic psychedelics, encompassing both natural and synthetic psychoactive compounds, are characterized by their action as agonists or partial agonists of serotonin 5-hydroxytryptamine 2A receptors. In this comprehensive review, we summarize the latest clinical trials of classic psychedelics on depression and anxiety, attending to the patient demographics and methodology of each study.
View Article and Find Full Text PDFPrim Care Companion CNS Disord
January 2024
Medical students have few opportunities to lead patient groups during their clinical year. During the psychiatry clerkship, they are group observers and do not have the skills to lead psychotherapy or treatment groups. This report describes a bingo group led by medical students on an inpatient psychiatry unit.
View Article and Find Full Text PDFPrim Care Companion CNS Disord
March 2019
Objective: For 8 years, Albert Einstein College of Medicine students have worked with the Bronx Psychiatric Center Assertive Community Treatment (ACT) team. We relate the medical student ACT team experience using the ratings and words of the students themselves. We describe the history, evolution, and structure of this novel program.
View Article and Find Full Text PDFSchizophrenia is a mental disorder that is characterized by progressive cognitive impairment in areas of attention, working memory, and executive functioning. Although no clear etiology of schizophrenia has been discovered, many factors have been identified that contribute to the development of the disease, such as neurotransmitter alterations, decreased synaptic plasticity, and diminished hippocampal volume. Historically, antipsychotic medications have targeted biochemical alterations in the brains of patients with schizophrenia but have been ineffective in alleviating cognitive and hippocampal deficits.
View Article and Find Full Text PDFAutophagy, the process of degrading intracellular components in lysosomes, plays an important role in the central nervous system by contributing to neuronal homeostasis. Autophagic failure has been linked to neurologic dysfunction and a variety of neurodegenerative diseases. Recent investigation has revealed a novel role for autophagy in the context of mental illness, namely in schizophrenia.
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January 2017
Since the first description of Seasonal Affective Disorder (SAD) by Rosenthal et al. in the 1980s, treatment with daily administration of light, or Bright Light Therapy (BLT), has been proven effective and is now recognized as a first-line therapeutic modality. More recently, studies aimed at understanding the pathophysiology of SAD and the mechanism of action of BLT have implicated shifts in the circadian rhythm and alterations in serotonin reuptake.
View Article and Find Full Text PDFObjective: Formal training for residents-as-teachers in psychiatry is increasingly emphasized. However, little is known about the quantity and content of residents' teaching, their attitudes toward teaching, or the training received on how to teach.
Methods: An online survey was disseminated to American and Canadian psychiatry residents.
Prim Care Companion CNS Disord
February 2015
Physical diseases are difficult to treat in psychiatric patients, whether they are comorbid disorders or mental disorders due to a general medical condition. The psychiatric symptoms are difficult to treat in a medical ward or clinic, and the physical symptoms are difficult to treat in a psychiatric ward or clinic. For this reason, medical-psychiatric units have been developed but remain uncommon.
View Article and Find Full Text PDFClozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection.
View Article and Find Full Text PDFPurpose: A longitudinal study to ascertain the attitudes toward, and habits of, substance use among a single class of medical students.
Method: A single class from a northeastern medical school was surveyed in both its first year (February 1991, 176 students) and its third year (May 1993, 170 students). The students were asked to report how frequently during the prior year they had used drugs or alcohol, and whether their use of each substance had increased, decreased, or remained the same since entering medical school; to identify any family members with histories of alcohol or drug problems; and to report any incidence during the prior year of ten behaviors associated with substance dependence.
Hosp Community Psychiatry
October 1983
The role assigned to the family in the treatment of the mentally ill has varied over the last 150 years; in some eras families were excluded from the patients' care and assigned a major share of blame for their illness. With more recent trends such as the self-help movement, consumer activism, and psychoeducation, the family is once again acknowledged as an important resource in the care of the chronically ill. One result is a proliferation of books written by and for the mentally ill and their families.
View Article and Find Full Text PDFAm J Roentgenol Radium Ther Nucl Med
November 1974
Am J Roentgenol Radium Ther Nucl Med
December 1972
Am J Roentgenol Radium Ther Nucl Med
July 1972
Am J Roentgenol Radium Ther Nucl Med
July 1972