Publications by authors named "W Zeck"

Article Synopsis
  • - The study investigates the effectiveness of a capacity-strengthening package to promote the use of heat-stable carbetocin (HSC) and tranexamic acid (TXA) in preventing and treating postpartum hemorrhage (PPH) in basic obstetric clinics in Uganda during crisis situations.
  • - A total of 2,299 women participated over a year, showing that while the use of prophylactic uterotonics was high, the introduction of HSC contributed to changes in the overall treatment practices, with a notable increase in TXA usage.
  • - The results highlight that enhancing healthcare provider capabilities can lead to improved management of PPH, suggesting critical implications for global health strategies in humanitarian settings.
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Article Synopsis
  • The study assesses the impact of a capacity-strengthening package on the use of medications for preventing and treating postpartum hemorrhage (PPH) in South Sudan's basic maternity facilities.
  • The implementation involved a series of phases introducing therapeutic protocols, including training and resources, resulting in improved use of uterotonics and a notable increase in PPH diagnoses.
  • Findings indicate a transition in medication usage patterns, with oxytocin usage decreasing as heat-stable carbetocin and tranexamic acid were introduced, highlighting the need for effective PPH management strategies in crisis-affected areas.
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Tranexamic acid (TXA) effectively reduces bleeding in women with postpartum hemorrhage (PPH) in hospital settings. To guide policies and practices, this rapid scoping review undertaken by two reviewers aimed to examine how TXA is utilized in lower-level maternity care settings in low-resource settings. Articles were searched in EMBASE, MEDLINE, Emcare, the Maternity and Infant Care Database, the Joanna Briggs Institute Evidence-Based Practice Database, and the Cochrane Library from January 2011 to September 2021.

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Heat-stable carbetocin (HSC), a long-acting oxytocin analogue that does not require cold-chain transportation and storage, is effective in preventing postpartum haemorrhage (PPH) in vaginal and caesarean deliveries in tertiary-care settings. We aimed to identify literature documenting how it is implemented in resource-limited and lower-level maternity care settings to inform policies and practices that enable its introduction in these contexts. A rapid scoping review was conducted with an 8-week timeframe by two reviewers.

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