Publications by authors named "W Yen"
Water energy-converting techniques that focus on interfacial charge separation and transfer have aroused significant attention. However, the water-repelling nature leads to a less dense liquid layer and a sharp gradient of liquid velocity, which limits its output performance. Here, a water sliding generator (WSG) based on a smooth liquid-like/semiconductor surface (SLSS) is developed that harnesses the full advantage of liquid sliding friction.
View Article and Find Full Text PDFArticle Synopsis
- Trimethylamine-oxide (TMAO) is emerging as a key biomarker for early thrombosis detection, but current testing methods are too complex and costly for home use.
- This study introduces a new MEMS-based biosensor capable of detecting TMAO in urine or serum samples with high sensitivity, rapid response time, and low drift, making it suitable for point-of-care applications.
- The biosensor achieves a conversion rate of 88% for TMAO and shows excellent selectivity for its by-product TMA, enabling effective pre-screening for cardiovascular risks linked to thrombosis.
Collagen plays a critical role in regulating breast cancer progression and therapeutic resistance. An improved understanding of both the features and drivers of tumor-permissive and -restrictive collagen matrices are critical to improve prognostication and develop more effective therapeutic strategies. In this study, using a combination of in vitro, in vivo and bioinformatic experiments, we show that type III collagen (Col3) plays a tumor-restrictive role in human breast cancer.
View Article and Find Full Text PDFArticle Synopsis
- The article reviews the effects of recreational drug use, specifically cannabis and opioids, on musculoskeletal health and bone density in patients with chronic pain.
- A total of 55 studies were analyzed, showing that these substances negatively impact bone maintenance by affecting bone cell activity and hormone production, leading to lower bone density and higher fracture risk.
- The authors conclude that while there is evidence of harm from recreational drugs on bone health, more research is needed to understand long-term effects and to improve treatment plans for those using these substances.
Article Synopsis
- Post-natal skin wound healing typically results in collagen-rich scars that don't fully function like the original tissue.
- This study identifies type III collagen (Col3) as crucial for controlling how wounds heal and whether scars form, using various animal models with different Col3 levels.
- Findings suggest that Col3 influences the structure of collagen fibers in scars and alters how cells respond to their physical environment, which could lead to improved strategies for better wound healing in clinical settings.