Publications by authors named "W Yasaka"
HPLC stability-indicating method was validated for Vitamin C (ascorbic acid) in semisolid pharmaceutical/cosmetic formulations containing glutathione and sodium metabisulfite, as antioxidants. The described procedure included a reliable, precise, accurate and specific method determination employing a 250mm x 4.6mm C(18) column, 0.
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- Vitamin C plays a crucial role in skin health through collagen synthesis, depigmentation, and antioxidant effects, but it is highly unstable in various conditions, necessitating effective antioxidant systems for stability in cosmetic products.
- The research aimed to develop O/W emulsions and aqueous gels containing vitamin C, testing the effects of antioxidants sodium metabisulfite (SMB) and glutathione (GLT) on its stability.
- Stability tests showed that formulations with SMB or GLT maintained over 90% of vitamin C content under controlled conditions, confirming that these antioxidants are essential for preserving vitamin C in cosmetics.
1. Pharmacokinetic parameters were determined for acetylsalicylic acid (ASA) and salicylic acid (SA) in plasma and lymph following the intravenous or oral administration of a water-soluble preparation of lysine-acetylsalicylic acid to dogs. 2.
View Article and Find Full Text PDFA single i.v. dose (5 mg/kg) of a light lanthanon, praseodymium, prolonged the duration of hexobarbital-induced sleep and zoxazolamine-induced paralysis, as well as it modified pharmacokinetic parameters of hexobarbital and zoxazolamine, in rats.
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