Publications by authors named "W Wohlgemuth"
Article Synopsis
- - The new treatment method, Bleomycin ElectroScleroTherapy (BEST), uses bleomycin and electrical pulses to improve the treatment of vascular malformations, drawing parallels to electrochemotherapy for tumors.
- - A Current Operating Procedure (COP) is being developed to standardize BEST clinical practices, utilizing the Cliniporator device for electrical stimulation, and following European guidelines for safety and efficacy.
- - The protocol outlines specific requirements and recommends two technical approaches based on the type of lesion and available resources: one using ultrasound guidance and the other combining ultrasound with fluoroscopy.
Necrotizing pancreatitis with superinfection of necrotic tissue is associated with a high rate of complications and mortality. The step-up approach is a well-established treatment strategy for necrotizing pancreatitis, emphasizing minimally invasive and endoscopic interventions before considering surgical options. Minimally invasive strategies often involve percutaneous drainage of collections, which carries the risk of persisting cutaneous pancreatic fistulas.
View Article and Find Full Text PDFThe invention of flow diverting stents (FDS) is a novel milestone in the field of endovascular aneurysm therapy, promoting physiological healing of the vessel segment contrary to prior deconstructive treatment strategies, such as coiling. The effects of FDS are based on changes in flow patterns, segmental wall stabilization, and the growth of a neointima. Although flow diversion is already well established for cerebral aneurysms in proximal segments, peripheral locations remain challenging.
View Article and Find Full Text PDFArteriovenous malformations (AVM) are benign vascular anomalies prone to pain, bleeding, and progressive growth. AVM are mainly caused by mosaic pathogenic variants of the RAS-MAPK pathway. However, a causative variant is not identified in all patients.
View Article and Find Full Text PDFArticle Synopsis
- Hypodense volumes (HDV) in mediastinal masses were identified in 29.7% of Hodgkin lymphoma patients analyzed from a study involving 1178 staging CT scans.
- These HDVs were predominantly found in larger tumor volumes and exhibited various patterns, including single lesions in 69.4% of cases and well delineated lesions in 70.1% of cases.
- Patients with HDV displayed more severe symptoms and had a lower 5-year progression-free survival rate (79.6% for HDV > 40 ml) compared to those with lower HDV levels, indicating a potential connection between HDV presence and poorer prognosis in Hodgkin lymphoma.