Human umbilical cord mesenchymal stromal cells promotes the proliferation and osteogenic differentiation of autologous bone marrow stem cells by secreting exosomes.

Fractures are frequently encountered diseases troubling the senior population, and the research on fracture repair and the exploration of effective treatment methods are of great significance. This study aimed to clarify the effect of human umbilical cord mesenchymal stromal cell-derived extracellular vesicles (hUMSC-EVs) on the proliferation and osteogenic differentiation of autologous bone marrow stem cells (ABMSCs). The two kinds of cells were co-cultured firstly, 5-Ethynyl-2'- deoxyuridine (EDU) staining and alizarin red staining were used to detect the proliferation and osteogenic differentiation of ABMSCs.

Spectrophotometric studies and application on the beta-type complex of Y-CPApK.

The beta-type complex formed between yttrium and p-carboxychlorophosphonazo (CPApK) has been studied. It was found that Y-CPApK complex can give a maximum absorptivity in a buffer media of HAc-NaAc ranging from pH 3.5-4.

Determination of azithromycin in human plasma by LC-MS-MS and its pharmacokinetics.

A LC-MS-MS assay has been developed for determinating of azithromycin in human plasma and investigating the pharmacokinetics in Chinese male volunteers following oral administration of a single dose of the capsules (0.5 g). Plasma samples were deproteinated by methanol and a liquid chromatographic-mass-mass spectrometric assay was developed for the determination of azithromycin in human plasma.