Molecular Epidemiological Characterization of and Clinical Isolates from a National Tertiary Care Hospital in Myanmar: Co-Isolation of Multiple Clones and Identification of Novel Staphylocoagulase Genotype.

Spread of antimicrobial resistance and virulence factors among / poses a potential public health concern in Myanmar. In this study, a total of 226 clinical isolates of ( = 211) and ( = 15) collected in Yangon General Hospital during a two-year period were analyzed for their antimicrobial susceptibility and genetic features. Methicillin-resistant (MRSA) accounted for 19% of isolates, associated with mostly staphylococcal cassette chromosome (SCC) type IV, or V.

Myiasis in Ulcerated Breast Carcinoma: First Case Record in Myanmar.

Myiasis is an infestation of maggot, which is frequently associated with poor personal hygiene and environmental sanitation. A 78-year-old female breast cancer patient visited clinic complaining of irritation, itching, and pain within the ulcerous cancer lesion for 3 weeks. Many maggots were found in the lesion.

Prevalence of Extended-Spectrum Beta-Lactamase/Carbapenemase Genes and Quinolone-Resistance Determinants in Clinical Isolates from Respiratory Infections in Myanmar.

In recent years, nosocomial infections due to multidrug resistant strains have been increasing, associated with growing trend of resistance to beta-lactams and fluoroquinolones (FQs) worldwide. In this study, prevalence of beta-lactamase genes and resistance mechanisms to FQ were analyzed in 191 clinical isolates derived from respiratory tract infections in a teaching hospital in Yangon, Myanmar. The major extended-spectrum beta-lactamase gene was , which was detected in 33% of isolates, with CTX-M-15 being dominant.

Genetic Diversity of CMY Beta-Lactamase Genes in Clinical Isolates of in Myanmar: Identification of Three Novel Types and Updated Phylogenetic Classification of .

The dissemination of CMY-type enzymes, one of the plasmid-mediated AmpC beta-lactamases, among Enterobacteriaceae has become an important public health concern. In this study, genetic diversity of CMY beta-lactamase genes was investigated for 50 -positive isolates detected from 426 clinical isolates of in Yangon, Myanmar. CMY genes were differentiated into 9 types, with being predominant (22 isolates, 44%), followed by , , , and included three novel types (CMY-156, CMY-158, CMY-159).