Publications by authors named "W W Ku"

Background: The optimal myopia control measures for children with intermittent exotropia (IXT) have yet to be determined. This study evaluates the impact of Repeated low-level red-light therapy (RLRL) on myopia control in this population.

Methods: This retrospective study included 94 participants divided into three groups: Myopic children without strabismus receiving RLRL treatment (RLRL Group).

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Integrating functional proteomics and next-generation sequencing (NGS) offers a comprehensive approach to unraveling the molecular intricacies of breast cancer. This study investigates the functional interplay between genomic alterations and protein expression in Taiwanese breast cancer patients. By analyzing 61 breast cancer samples using tandem mass tag (TMT) labeling and mass spectrometry, coupled with whole-exome sequencing (WES) or targeted sequencing, we identified key genetic mutations and their impact on protein expression.

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Article Synopsis
  • - The research focuses on improving the understanding of gene sets and pathways in biomedical data using enhanced gene lists called PAGs (pathways, annotated gene lists, and gene signatures), which include additional metadata to support biological insights.
  • - A new clustering method named todenE combines topology-based and density-based approaches to better identify groups of PAGs, creating clearer functional representations known as Super-PAGs, while utilizing Large Language Models (LLM) to enrich contextual information.
  • - Through performance comparisons and innovative metrics like the Disparity Index (DI), the study assesses different clustering methods, ultimately showing that todenE offers improved semantic quality and inclusivity in gene clustering when applied to various datasets.
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Background And Aim: The COVID-19 pandemic has led to a significant adverse effect on the mental health of healthcare professionals. This study aims to assess the effects of the prolonged pandemic on burnout and mood disorders and to evaluate the influence of positive vaccination beliefs on these factors at a medical center during the extended COVID-19 pandemic.

Methods: This retrospective study analyzed the results of an online questionnaire survey including burnout status and mood disorders from 2020 to 2022.

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