Extracellular vesicles release from protozoa parasite and animal model.

Diseases caused by protozoan parasites, such as leishmaniasis, trypanosomiasis, and malaria, are highly complex and together continue to cause high annual morbidity and mortality. The search for new compounds in environmental biodiversity, repositioning known drugs, and developing vaccines using old and innovative technologies have been employed to discover vaccines and new and alternative treatments. Extracellular vesicles (EVs) can carry parasite antigens, creating a new possibility to develop an effective and affordable platform for treatment, vaccines, and drug delivery.

Synergistic Effects of Magnesium Oxide and SBR Latex Additives on Cement Sheath Stability in Oil Well Operations.

Leaks through cement sheaths remain a complex and challenging issue in the oil industry, representing a persistent obstacle that has endured for decades. The drying shrinkage, an inherent characteristic of Portland cement, substantially exacerbates this problem, driving the formation of microcracks and heightened permeability under variable stress conditions. In this context, additives emerge as significant elements in addressing this issue, offering a pathway to mitigate the adverse effects of leaks.

Extracellular Vesicles Released by Promastigotes with Distinct Virulence Profile Differently Modulate the Macrophage Functions.

spp. is the aetiologic agent of leishmaniasis, a disease endemic in several developing countries. The parasite expresses and secretes several virulence factors that subvert the macrophage function and immune response.

Preparation and Characterization of a Coordination Polymer Based on Iron (III)-Cyamelurate as a Superior Catalyst for Heterogeneous Fenton-Like Processes.

We report on a new iron (iii)-cyamelurate-based coordination polymer. The new material based on a heptazine derivative was prepared in aqueous medium and characterized by a variety of techniques including TGA, FTIR, XRD, HRTEM, and STEM. Due to the high structural stability of the complex in aqueous media, its heterogeneous Fenton-like catalytic activity was evaluated using a model molecule.