Anxiolytic, Antidepressant, and Anticholinesterase Effects of Essential Oil from (G.Mey.) DC.

Aromatic plants are rich sources of essential oils (EOs), recognized for their therapeutic properties due to their diversity of phytochemicals. This study investigated the anxiolytic and antidepressant effects of essential oil (MsEO) through inhalation in an animal model and its in vitro anticholinesterase (AChE) activity. The EO was obtained by hydrodistillation, and its volatile constituents were analyzed by GC-MS.

Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study.

Objective: To evaluate the association between the risk of death from COPD and air temperature events in ten major Brazilian microregions.

Methods: This was a time series analysis of daily COPD deaths and daily mean air temperatures between 1996 and 2017. Using distributed nonlinear lag models, we estimated the cumulative relative risks of COPD mortality for four temperature percentiles (representing moderate and extreme cold and heat events) in relation to a minimum mortality temperature, with a lag of 21 days, in each microregion.

Development of multi-scale indices of human mobility restriction during the COVID-19 based on air quality from local and global NO concentration.

This study investigated whether variability in air quality, especially related to vehicular emissions, during the COVID-19 pandemic could indicate social distancing. Data from measurements and satellite estimates were used. The study areas were São Paulo, Brazil, and Bologna, Italy.

Smoking induces increased apoptosis in osteoblasts: changes in bone matrix organic components.

Clinical studies demonstrate the impact of smoking on bone tissue fragility and higher incidence of fractures. However, it is not totally understood which physiological mechanisms could be involved in these events. Previously, we showed important changes in bone tissue components in experimental model of cigarette smoke (CS) exposure.

The effect of air temperature on mortality from cerebrovascular diseases in Brazil between 1996 and 2017.

Cerebrovascular diseases (CVD) are one of the leading causes of mortality globally. Air temperature is one of the risk factors for CVD; however, few studies have investigated the relationship between air temperature and mortality from these diseases in Brazil. This time series study investigated the relationship between air temperature and CVD mortality in 10 microregions located across Brazil's five regions during the period 1996 to 2017 using mortality data from the national health information system, DATASUS and daily mean temperature data.