Publications by authors named "W U Ombelet"
Infertility affects millions worldwide, with significant medical, financial, and emotional challenges, particularly in low- and middle-income countries (LMICs). Cultural, religious, financial, and gender-related barriers hinder access to treatment, exacerbating social and economic consequences, especially for women. Despite its prevalence, infertility often remains overlooked due to competing health priorities.
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- The study investigates the short- and long-term impacts of SARS-CoV-2 on sperm quality, revealing a lack of established knowledge due to insufficient longitudinal research.
- Evaluating sperm parameters included assessments like motility, morphology, DNA damage, and the presence of anti-sperm antibodies, which classified patients based on their antibody response post-infection.
- Findings indicate that SARS-CoV-2 affects various sperm quality metrics, with most changes being temporal and suggesting that individual immune response levels influence recovery to baseline sperm quality after infection.
Background: We developed a simplified IVF culture system (SCS) which has proven to be effective and safe in a selected IVF cohort.
Methods: Preterm birth (PTB) and low birth weight (LBW) of 175 singletons born after using the SCS, 104 after fresh embryo transfer (ET), and 71 after frozen embryo transfer, were compared with all singletons born in Flanders between 2012 and 2020 conceived after natural conception, ovarian stimulation (OS), and assisted reproduction (IVF/ICSI).
Findings: The proportion of preterm (<37 weeks) births was significantly higher in the case of IVF or ICSI, followed by hormonal treatment, compared to spontaneous pregnancies.
Background: Assisted reproductive techniques services are often not accessible to the majority of infertile couples in Low and Middle Income Countries (LMIC) due to high costs. Lowering IVF laboratory costs is a crucial step to make IVF affordable for a larger part of the world population. We developed a simplified culture system (SCS) which has proven to be effective, and the next step is to prove its safety.
View Article and Find Full Text PDFStudy Question: What is the impact of BMI on uncomplicated pregnancies and healthy births in women who did or did not have medically assisted reproduction (MAR, i.e. ART or hormonal stimulation without manipulation of eggs or embryos) in the Flanders region (Belgium)?
Summary Answer: Women with a higher BMI who use MAR are at the highest risk of pregnancy and birth complications.