Publications by authors named "W Truin"
Background: Differences in estrogen (ER) and progesterone (PR) expression between invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) could be an underlying reason for the difference in chemo-sensitivity and response to hormonal therapy between ILC and IDC. The aim of this study was to investigate the differences in ER and PR expression levels between postmenopausal patients with hormonal receptor-positive ILC and IDC.
Methods: We included all ER and/or PR receptor-positive ILC and IDC, diagnosed between January 2011 and December 2013 from the population-based Netherlands Cancer Registry.
Introduction: This study describes the differences between the two largest histological breast cancer subtypes (invasive ductal carcinoma (IDC) and invasive (mixed) lobular carcinoma (ILC) with respect to patient and tumor characteristics, treatment-choices and outcome in metastatic breast cancer.
Results: Patients with ILC were older at diagnosis of primary breast cancer and had more often initial bone metastasis (46.5% versus 34.
Article Synopsis
- Sentinel lymph node (SLN) biopsy is the standard method for staging axillary lymph nodes in invasive breast cancer, with advancements in pathology and TNM classification influencing outcomes.
- From 1998 to 2013, a study analyzed the effects of SLN biopsy on axillary node status in patients with invasive lobular carcinoma (ILC) compared to invasive ductal carcinoma (IDC).
- The results revealed that patients with ILC were more likely to have isolated tumor cells (ITCs) in their axillary nodes than those with IDC, indicating a need for further research to understand the clinical implications of these findings.
Background: This study was conducted to determine the impact of neoadjuvant chemotherapy (NAC) on the likelihood of breast-conserving surgery (BCS) performed for patients with invasive lobular breast carcinoma (ILC) and invasive ductal carcinoma (IDC).
Methods: Female patients with a diagnosis of ILC or IDC in The Netherlands between July 2008 and December 2012 were identified through the population-based Netherlands Cancer Registry.
Results: A total of 466 ILC patients received NAC compared with 3622 IDC patients.
Purpose: The aim of this study was to compare the frequency of breast-conserving surgery (BCS) between early-stage invasive ductal (IDC) and invasive lobular breast cancer (ILC).
Methods: Women with primary non-metastatic pT1 and pT2 IDC or ILC diagnosed between 1990 and 2010 were selected from the NCR. All patients underwent BCS or primary mastectomy without neoadjuvant treatment and proportions per year were calculated.