[The role of computerized rheoencephalography in the assessment of normal pressure hydrocephalus. Preliminary report].

Background And Purpose: It is generally agreed that the positive result of lumbar cerebrospinal fluid (CSF) withdrawal offers a reliable means for selection of patients likely to respond to shunting in normal pressure hydrocephalus (NPH). However the studies of cerebral hemodynamics in NPH are performed Routinely only in few neurosurgical centers. We therefore studied the effect of CSF withdrawal on cerebrovascular autoregulation (CVA) in this condition by means of computerized rheoencephalography [REG].

The role of computerized rheoencephalography in the assessment of normal pressure hydrocephalus.

The aim of this study was to determine the relationship between arterial compliance derived from rheoencephalography (REG), and the slope of the regression line between pulse amplitude and mean ICP (AMP/P) recorded during a lumbar infusion study. A hypothetical link between these two variables has been suggested in the past. Resistance to the outflow of cerebrospinal fluid (R(out)) and the slope of the amplitude pressure regression line (AMP/P) were calculated in 62 patients diagnosed with posttraumatic normal pressure hydrocephalus (NPH).

[Prognostic value of computerized rheoencephalography in chronic posttraumatic subdural hematoma: a preliminary report].

Background And Purpose: The results of treatment of chronic subdural hematoma (CSDH) are still regarded as unsatisfactory. Measurements of cerebral hemodynamics are increasingly used to elucidate the pathophysiology of mental disturbances and hemiparesis in CSDH. On the other hand the clinical studies of cerebrovascular autoregulation in this condition are almost nonexistent.

[Circadian rhythms of melatonin of patients with severe traumatic brain injury].

The study was performed on a group of 5 patients with severe traumatic brain injury and in 2 healthy volunteers as the controls. The examination began 2-5 days after injury. The management of the patients and controls did not affect the natural melatonin circadian rhythm.

[Association of apoE polymorphism and treatment outcome in patients with traumatic brain injury].

A number of papers published in recent years indicate the importance of the apolipoprotein E gene (apoE) for the outcome of traumatic brain injury [TBI]. A majority of publications suggest that the presence of an epsilon 4 allele is associated with an unfavorable long-term outcome. A hypothesis has been recently posed that this phenomenon may be related to an increased risk of traumatic hypoxic brain damage or post-traumatic ischemic complications.