Influenza virus evolution and defective genome formation are shaped by host genotype and sex.

Host-specific factors, including genetic background and sex, shape viral adaptation and influence virulence, yet their interactions and quantitative effects remain poorly understood. Additionally, multiple infections, where a host is infected with viruses from more than one source, are hypothesized to enhance viral diversity and increase virulence, but their impact in vertebrate hosts remains largely unexplored. We experimentally adapted influenza A virus (IAV) to male and female BALB/c and C57BL/6 mice under single and multiple infection conditions.

Nicotine Metabolite Ratio in People with HIV Who Smoke Cigarettes Receiving Pharmacologic and Behavioral Cessation Therapy.

People with human immunodeficiency virus (HIV; PWH) smoke cigarettes at triple the rate of the general population in the United States. Efforts to increase quit rates in this group have met with limited success. The nicotine metabolite ratio (NMR) has shown promise as a phenotypic marker that may be useful in selecting the most appropriate cessation treatments for people who smoke cigarettes.

Revisiting the description of Atractoscion macrolepis (Perciformes: Sciaenidae): Another argument for comprehensive taxonomy.

Atractoscion macrolepis was described as a species separate to A. aequidens, distinguished by a geographically-separated distribution, genetic evidence and a diagnostic meristic character: the number of pored lateral line scales. However, the distinction of these species and description of A.

Efficacy of Smoking Cessation Interventions among People with HIV in Kenya.

Background: People with human immunodeficiency virus (HIV) smoke at much higher rates than the general population, resulting in higher risk for tobacco-related morbidity and mortality. The efficacy of smoking cessation interventions among people with HIV in lower-middle-income countries remains unclear.

Methods: We conducted a randomized, 2 × 2 factorial design trial based in Nairobi, Kenya, to evaluate the efficacy of bupropion versus placebo, and a culturally tailored behavioral cessation therapy, called Positively Smoke Free (PSF), versus standard of care for people with HIV who smoke.

Inland recreational fisheries contribute nutritional benefits and economic value but are vulnerable to climate change.

Inland recreational fishing is primarily considered a leisure-driven activity in freshwaters, yet its harvest can contribute to food systems. Here we estimate that the harvest from inland recreational fishing equates to just over one-tenth of all reported inland fisheries catch globally. The estimated total consumptive use value of inland recreational fish destined for human consumption may reach US$9.